OMIA 000629-9913 : Megacolon in Bos taurus |
In other species:
domestic cat
,
horse
,
pig
,
rabbit
Possibly relevant human trait(s) and/or gene(s)s (MIM numbers):
600155 (trait)
,
277580 (trait)
,
600501 (trait)
,
131244 (gene)
Mendelian trait/disorder:
unknown
Considered a defect:
yes
Cross-species summary:
Also known as Hirschsprung disease. A disorder in which the large intestine (caecum, colon and sometimes the rectum) undergoes a large dilation and fills with faecal mass. Associated with incomplete migration of nerve cells to the intestine during embryonic development, resulting in lack of peristalsis and hence a build-up of faecal material.
Reference
2005 | Forzán, M.J., McClure, J.T. : | |
Congenital aganglionosis in a 3-day-old Holstein calf. Can Vet J 46:342-4, 2005. Pubmed reference: 15943121. |
Edit History
- Created by Frank Nicholas on 18 Sep 2005