OMIA 000649-8128 : Microphthalmia in Oreochromis niloticus

In other species: chicken , dog , pig , Eastern wapiti , cattle , sheep , golden hamster , Campbell's desert hamster , water buffalo

Mendelian trait/disorder: yes

Considered a defect: yes

Key variant known: no

Cross-species summary: Abnormal smallness in all dimensions of one or both eyes.

Inheritance: CRISPR/Cas9 gene editing was used to create mutations (GMO).

Clinical features: Hyperpigmentation body phenotype and microphthalmia

Associated gene:

Symbol Description Species Chr Location OMIA gene details page Other Links
GATA2A Oreochromis niloticus - no genomic information (-..-) GATA2A Ensembl

Reference


2021 Wang, C., Lu, B., Li, T., Liang, G., Xu, M., Liu, X., Tao, W., Zhou, L., Kocher, T.D., Wang, D. :
Nile tilapia: A model for studying teleost color patterns. J Hered 112:469-484, 2021. Pubmed reference: 34027978. DOI: 10.1093/jhered/esab018.

Edit History


  • Created by Imke Tammen2 on 26 May 2021
  • Changed by Imke Tammen2 on 26 May 2021