OMIA:000649-8128 : Microphthalmia in Oreochromis niloticus (Nile tilapia) |
In other species: chicken , dog , pig , Eastern wapiti , taurine cattle , sheep , golden hamster , fox squirrel , Campbell's desert hamster , water buffalo
Categories: Vision / eye phene
Links to MONDO diseases: No links.
Mendelian trait/disorder: yes
Considered a defect: yes
Key variant known: no
Cross-species summary: Abnormal smallness in all dimensions of one or both eyes.
Inheritance: CRISPR/Cas9 gene editing was used to create mutations (GMO).
Clinical features: Hyperpigmentation body phenotype and microphthalmia
Associated gene:
| Symbol | Description | Species | Chr | Location | OMIA gene details page | Other Links |
|---|---|---|---|---|---|---|
| GATA2A | Oreochromis niloticus | LG5 | NC_031970.2 (30193896..30180310) | GATA2A | Homologene, Ensembl , NCBI gene |
Cite this entry
Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2021). OMIA:000649-8128: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70
References
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
| 2023 | Liu, X., Zhou, L., Li, W., Wu, J., Wang, D. : |
| Gata2a mutation causes progressive microphthalmia and blindness in Nile tilapia. Int J Mol Sci 24:, 2023. Pubmed reference: 36834978 . DOI: 10.3390/ijms24043567. | |
| 2021 | Wang, C., Lu, B., Li, T., Liang, G., Xu, M., Liu, X., Tao, W., Zhou, L., Kocher, T.D., Wang, D. : |
| Nile tilapia: A model for studying teleost color patterns. J Hered 112:469-484, 2021. Pubmed reference: 34027978 . DOI: 10.1093/jhered/esab018. |
Edit History
- Created by Imke Tammen2 on 26 May 2021
- Changed by Imke Tammen2 on 26 May 2021