OMIA:000649-9615 : Microphthalmia in Canis lupus familiaris (dog)

In other species: Nile tilapia , chicken , pig , Eastern wapiti , taurine cattle , sheep , golden hamster , fox squirrel , Campbell's desert hamster , water buffalo

Categories: Vision / eye phene

Links to MONDO diseases: No links.

Mendelian trait/disorder: unknown

Considered a defect: yes

Cross-species summary: Abnormal smallness in all dimensions of one or both eyes.

Genetic engineering: Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2023). OMIA:000649-9615: Online Mendelian Inheritance in Animals (OMIA) [dataset].


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2021 Genetics Committee of the American College of Veterinary Opthalmologists :
The Blue Book: Ocular disorders presumed to be inherited in purebred dogs. 13th Edition , 2021.
2019 Shaw, G.C., Tse, M.P.Y., Miller, A.D. :
Microphthalmia with multiple anterior segment defects in Portuguese Water Dogs. Vet Pathol 56:269-273, 2019. Pubmed reference: 30131012. DOI: 10.1177/0300985818794248.
1997 Lohmann, B., Klesen, S. :
Cataract and microphthalmia in a litter of Russian Terriers [German] Praktische Tierarzt 78:981 ff., 1997.
1994 Shastry, B.S., Reddy, V.N. :
Studies on congenital hereditary cataract and microphthalmia of the miniature Schnauzer dog Biochemical and Biophysical Research Communications 203:1663-1667, 1994. Pubmed reference: 7945315. DOI: 10.1006/bbrc.1994.2377.
1991 Zhang, R.L., Samuelson, D.A., Zhang, Z.G., Reddy, V.N., Shastry, B.S. :
Analysis of Eye Lens-Specific Genes in Congenital Hereditary Cataracts and Microphthalmia of the Miniature Schnauzer Dog Investigative Ophthalmology & Visual Science 32:2662-2665, 1991. Pubmed reference: 1869417.
1983 Gelatt, KN., Samuelson, DA., Bauer, JE., Das, ND., Wolf, ED., Barrie, KP., Andresen, TL. :
Inheritance of congenital cataracts and microphthalmia in the Miniature Schnauzer. Am J Vet Res 44:1130-2, 1983. Pubmed reference: 6870020.
1981 Gelatt, K.N., Powell, G., Huston, K. :
Inheritance of microphthalmia with coloboma in the Australian shepherd dog. American Journal of Veterinary Research 42:1686-1690, 1981. Pubmed reference: 7325429.
1973 Gelatt, K.N., McGill, L.D. :
Clinical characteristics of microphthalmia with colobomas of the Australian Shepherd dog Journal of the American Veterinary Medical Association 162:393-396, 1973. Pubmed reference: 4691375.
1959 Barone, R., Lescure, F. :
[Heterochromia and microphthalmia in the dog] Review Medicine Veterinaire 110:769-792, 1959.

Edit History

  • Created by Frank Nicholas on 06 Sep 2005
  • Changed by Imke Tammen2 on 17 Jun 2023