OMIA 000679-9940 : Muscular dystrophy in Ovis aries

In other species: chicken , dog , turkey , American mink , domestic cat

Possibly relevant human trait(s) and/or gene(s) (MIM number): 310200

Mendelian trait/disorder: yes

Considered a defect: yes

Key variant known: no

Cross-species summary: Degenerative muscle disorder, leading to muscle weakness, liberation of myoglobin into the circulation from skeletal muscle, and subsequent wasting and possible contracture.

References


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
1997 Johnsen, R.D., Laing, N.G., Huxtable, C.R., Kakulas, B.A. :
Normal expression of adhalin and merosin in ovine congenital progressive muscular dystrophy Australian Veterinary Journal 75:215-216, 1997. Pubmed reference: 9088516.
1990 Nakada, H., Jacobsen, P.F., Johnsen, R.D., Kakulas, B.A. :
Positive Immunostaining of Ovine Congenital Progressive Muscular Dystrophy with Antibody Against N-Terminal and C- Terminal Dystrophin Australian Veterinary Journal 67:271-272, 1990. Pubmed reference: 2203334.
1989 Richards, R.B., Passmore, I.K. :
Ultrastructural Changes in Skeletal Muscle in Ovine Muscular Dystrophy Acta Neuropathologica 79:168-175, 1989. Pubmed reference: 2596265.
1988 Richards, R.B., Lewer, R.P., Passmore, I.K., McQuade, N.C. :
Ovine congenital progressive muscular dystrophy: mode of inheritance Australian Veterinary Journal 65:93-94, 1988. Pubmed reference: 3401155.
1974 McGavin, M.D. :
An animal model of human disease: progressive ovine muscular dystrophy Comparative Pathology Bulletin 6:3-4, 1974.
1954 Morley, F.H.W. :
A new lethal factor in Australian Merino sheep Australian Veterinary Journal 30:237-240, 1954.

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  • Created by Frank Nicholas on 06 Sep 2005