OMIA:000748-29064 : Osteochondritis dissecans in Uncia uncia (snow leopard) |
Categories: Skeleton phene (incl. short stature & teeth)
Mendelian trait/disorder: unknown
Disease-related: yes
Key variant is published: no
Cross-species summary: "A joint disorder caused by blood deprivation in the subchondral bone causing the subchondral bone to die in a process called avascular necrosis. The bone is then reabsorbed by the body, leaving the articular cartilage it supported prone to damage. The result is fragmentation (dissection) of both cartilage and bone, and the free movement of these osteochondral fragments within the joint space, causing pain and further damage" [HPO:0010886] Osteochondritis dissecans (OCD) is sometimes called osteochondrosis dissecans and is a more severe form of Osteochondrosis (OC) - see OMIA:000750.
Cite this entry
Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2012). OMIA:000748-29064: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70
Reference
2012 | Herrin, K.V., Allan, G., Black, A., Aliah, R., Howlett, C.R. : |
Stifle osteochondritis dissecans in snow leopards (Uncia uncia). J Zoo Wildl Med 43:347-54, 2012. Pubmed reference: 22779240. DOI: 10.1638/2010-0169.1. |
Edit History
- Created by Frank Nicholas on 22 Aug 2012