OMIA:000748-9796 : Osteochondritis dissecans in Equus caballus (horse)

In other species: dog , snow leopard

Categories: Skeleton phene (incl. short stature & teeth)

Mendelian trait/disorder: unknown

Considered a defect: yes

Cross-species summary: "A joint disorder caused by blood deprivation in the subchondral bone causing the subchondral bone to die in a process called avascular necrosis. The bone is then reabsorbed by the body, leaving the articular cartilage it supported prone to damage. The result is fragmentation (dissection) of both cartilage and bone, and the free movement of these osteochondral fragments within the joint space, causing pain and further damage" [HPO:0010886] Osteochondritis dissecans (OCD) is sometimes called osteochondrosis dissecans and is a more severe form of Osteochondrosis (OC) - see OMIA000750.

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2005). OMIA:000748-9796: Online Mendelian Inheritance in Animals (OMIA) [dataset].


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2024 Antunes, J., Salcedo-Jiménez, R., Lively, S., Potla, P., Coté, N., Dubois, M.S., Koenig, J., Kapoor, M., LaMarre, J., Koch, T.G. :
microRNAs are differentially expressed in equine plasma of horses with osteoarthritis and osteochondritis dissecans versus control horses. PLoS One 19:e0297303, 2024. Pubmed reference: 38394252. DOI: 10.1371/journal.pone.0297303.
2023 Sloan, P.B., White, B., Santschi, E.M. :
Racing performance of juvenile Thoroughbreds with femoropatellar osteochondrosis at auction: A retrospective case-control study. Equine Vet J , 2023. Pubmed reference: 37191294. DOI: 10.1111/evj.13943.
Zimmermann, E., Distl, O. :
SNP-based heritability of osteochondrosis dissecans in Hanoverian warmblood horses. Animals (Basel) 13:Article 1462, 2023. Pubmed reference: 37174498. DOI: 10.3390/ani13091462.
2016 James, O., Payne, R., Bathe, A., Greet, T., Wylie, C. :
Arthroscopy of the dorsal and plantar pouches of the tarsocrural joint for the treatment of osteochondritis dissecans in the horse: Clinical features and follow-up. Vet Surg 45:1049-1055, 2016. Pubmed reference: 27684059. DOI: 10.1111/vsu.12560.
2014 Desjardin, C., Chat, S., Gilles, M., Legendre, R., Riviere, J., Mata, X., Balliau, T., Esquerré, D., Cribiu, E.P., Betch, J.M., Schibler, L. :
Involvement of mitochondrial dysfunction and ER-stress in the physiopathology of equine osteochondritis dissecans (OCD). Exp Mol Pathol , 2014. Pubmed reference: 24657499. DOI: 10.1016/j.yexmp.2014.03.004.
2013 Hilla, D., Distl, O. :
Prevalence of osteochondral fragments, osteochondrosis dissecans and palmar/plantar osteochondral fragments in Hanoverian Warmblood horses. Berl Munch Tierarztl Wochenschr 126:236-44, 2013. Pubmed reference: 23758039.
Olstad, K., Hendrickson, E.H., Carlson, C.S., Ekman, S., Dolvik, N.I. :
Transection of vessels in epiphyseal cartilage canals leads to osteochondrosis and osteochondrosis dissecans in the femoro-patellar joint of foals; a potential model of juvenile osteochondritis dissecans. Osteoarthritis Cartilage 21:730-8, 2013. Pubmed reference: 23428601. DOI: 10.1016/j.joca.2013.02.005.
Wright, I.M., Minshall, G.J. :
Identification and treatment of osteochondritis dissecans of the distal sagittal ridge of the third metacarpal bone. Equine Vet J , 2013. Pubmed reference: 24102887. DOI: 10.1111/evj.12187.
2010 Lettry, V., Sumie, Y., Mitsuda, K., Tagami, M., Hosoya, K., Takagi, S., Okumura, M. :
Divergent diagnosis from arthroscopic findings and identification of CPII and C2C for detection of cartilage degradation in horses. Jpn J Vet Res 57:197-206, 2010. Pubmed reference: 20364792.
2009 Mählmann, C.h., Steiger, A. :
[Assessment of hereditary defects and dispositions of the horse under animal welfare aspects]. Schweiz Arch Tierheilkd 151:153-8, 2009. Pubmed reference: 19333900. DOI: 10.1024/0036-7281.151.4.153.
2002 Schoenborn, W.C., Rick, M.C., Hornof, W.J. :
Computed tomographic appearance of osteochondritis DISSECANS-like lesions of the proximal articular surface of the proximal phalanx in a horse Veterinary Radiology & Ultrasound 43:541-544, 2002. Pubmed reference: 12502107.
1999 Fubini, S.L., Erb, H.N., Freeman, K.P., Todhunter, R.J. :
Prognostic factors affecting survival of 507 horses with joint disease: (1983 to 1990) Canadian Journal of Veterinary Research - Revue Canadienne de Recherche Veterinaire 63:253-260, 1999. Pubmed reference: 10534004.
1998 Riley, C.B., Scott, W.M., Caron, J.P., Fretz, P.B., Bailey, J.V., Barber, S.M. :
Osteochondritis dessicans and subchondral cystic lesions in draft horses - a retrospective study Canadian Veterinary Journal - Revue Veterinaire Canadienne 39:627-633, 1998.
1996 Canonici, F., Serata, V., Buldini, A., Mascioni, A. :
134 horses with osteochondritis dissecans of the tarso-crural joint - clinical considerations and results following arthroscopic surgery Journal of Equine Veterinary Science 16:345-348, 1996.
Ralston, S.L. :
Hyperglycemia/hyperinsulinemia after feeding a meal of grain to young horses with osteochondritis dissecans (ocd) lesions Pferdeheilkunde 12:320-322, 1996.
1994 Campbellbeggs, C.L., Johnson, P.J., Messer, N.T., Lattimer, J.C., Johnson, G., Casteel, S.W. :
Osteochondritis Dissecans in an Appaloosa Foal Associated with Zinc Toxicosis Journal of Equine Veterinary Science 14:546-550, 1994.

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  • Created by Frank Nicholas on 06 Sep 2005