OMIA:000748-29064 : Osteochondritis dissecans in Uncia uncia (snow leopard)

In other species: dog , horse

Categories: Skeleton phene (incl. short stature & teeth)

Mendelian trait/disorder: unknown

Considered a defect: yes

Key variant is published: no

Cross-species summary: "A joint disorder caused by blood deprivation in the subchondral bone causing the subchondral bone to die in a process called avascular necrosis. The bone is then reabsorbed by the body, leaving the articular cartilage it supported prone to damage. The result is fragmentation (dissection) of both cartilage and bone, and the free movement of these osteochondral fragments within the joint space, causing pain and further damage" [HPO:0010886] Osteochondritis dissecans (OCD) is sometimes called osteochondrosis dissecans and is a more severe form of Osteochondrosis (OC) - see OMIA000750.

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2012). OMIA:000748-29064: Online Mendelian Inheritance in Animals (OMIA) [dataset].


2012 Herrin, K.V., Allan, G., Black, A., Aliah, R., Howlett, C.R. :
Stifle osteochondritis dissecans in snow leopards (Uncia uncia). J Zoo Wildl Med 43:347-54, 2012. Pubmed reference: 22779240.

Edit History

  • Created by Frank Nicholas on 22 Aug 2012