OMIA 000748-29064 : Osteochondritis dissecans in Uncia uncia

In other species: dog , horse

Mendelian trait/disorder: unknown

Considered a defect: yes

Key variant is published: no

Cross-species summary: A joint disorder caused by blood deprivation in the subchondral bone causing the subchondral bone to die in a process called avascular necrosis. The bone is then reabsorbed by the body, leaving the articular cartilage it supported prone to damage. The result is fragmentation (dissection) of both cartilage and bone, and the free movement of these osteochondral fragments within the joint space, causing pain and further damage [HPO:0010886], also called osteochondrosis dissecans

Reference


2012 Herrin, K.V., Allan, G., Black, A., Aliah, R., Howlett, C.R. :
Stifle osteochondritis dissecans in snow leopards (Uncia uncia). J Zoo Wildl Med 43:347-54, 2012. Pubmed reference: 22779240.

Edit History


  • Created by Frank Nicholas on 22 Aug 2012