OMIA 000754-9940 : Osteogenesis imperfecta, generic in Ovis aries

In other species: dog , domestic cat , cattle

Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 166210 (trait) , 166220 (trait) , 259420 (trait)

Mendelian trait/disorder: yes

Mode of inheritance: Autosomal Dominant

Considered a defect: yes

Key variant known: no

Cross-species summary: Abnormally brittle bones that fracture easily.


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
1992 Arthur, D.G., Thompson, K.G., Swarbrick, P. :
Lethal Osteogenesis Imperfecta and Skin Fragility in Newborn New-Zealand Romney Lambs New Zealand Veterinary Journal 40:112-116, 1992. Pubmed reference: 16031672. DOI: 10.1080/00480169.1992.35712.
1964 Holmes, J.R., Baker, J.R., Davies, E.T. :
Osteogenesis imperfecta in lambs Veterinary Record 76:980-984, 1964.
1963 Kater, J.C., Hartley, W.J., Dysart, T.H., Campbell, A.R. :
Osteogenesis imperfecta and bone resorption: two unusual skeletal abnormalities in young lambs New Zealand Veterinary Journal 11:41-46, 1963.

Edit History

  • Created by Frank Nicholas on 06 Sep 2005
  • Changed by Frank Nicholas on 03 Oct 2011