OMIA 000810-9823 : Polydactyly in Sus scrofa

In other species: domestic cat , cattle , chicken , dog , turkey , domestic guinea pig , goat , guanaco , Arabian camel , Western roe deer , horse , springbok , rock pigeon , sheep , llama , alpaca

Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 174500 (trait) , 605522 (gene)

Mendelian trait/disorder: no

Considered a defect: yes

Key variant known: no

Cross-species summary: Often called preaxial polydactyly (PPD)

Inheritance: Gorbach et al. (2010) provided convincing data that this disorder is inherited but could find no evidence of a single gene of large effect. A whole-genome scan with a SNP chip identified a 25 Mb region on chromosome SSC5 that appears to play some role in the development of this disorder.


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
2020 Ma, C., Khederzadeh, S., Adeola, A.C., Han, X.M., Xie, H.B., Zhang, Y.P. :
Whole genome resequencing reveals an association of ABCC4 variants with preaxial polydactyly in pigs. BMC Genomics 21:268, 2020. Pubmed reference: 32228435. DOI: 10.1186/s12864-020-6690-1.
2010 Gorbach, D., Mote, B., Totir, L., Fernando, R., Rothschild, M. :
Polydactyl Inheritance in the Pig. J Hered :, 2010. Pubmed reference: 20308080. DOI: 10.1093/jhered/esq037.
1963 Ptak, W. :
[Polydactyly in a wild boar] Acta Theriologica 6:312-314, 1963.
1959 Gaedtke, H. :
[Hereditary polydactyly in a pig family] Monatshefte fur Veterinarmedizin 14:57-58, 1959.
1938 Hughes, E. :
Polydactyly in swine Journal of Heredity 26:415-418, 1938.
1931 Curson, H. :
Polydactyly in a Springbok and a pig Anatomical Studies 19:853 only, 1931.

Edit History

  • Created by Frank Nicholas on 15 Jun 2010