OMIA 000823-9793 : Prognathism in Equus asinus

In other species: dog , horse , cattle

Possibly relevant human trait(s) and/or gene(s) (MIM number): 176700

Mendelian trait/disorder: unknown

Considered a defect: yes

Markers: Using a comparative candidate gene strategy, based on evidence from humans, Rodrigues et al. (2013) identified a SNP (g503G>A) in an intron of the MATN1 gene (encoding Matrilin-1) with a significant association with this disorder.

Breed: Zamorano-Leonés.

Reference


2013 Rodrigues, J.B., Araújo, S., Guedes-Pinto, H., San Roman, F., Viegas, C., Bastos, E. :
Analysis of new Matrilin-1 gene variants in a case-control study related to dental malocclusions in Equus asinus. Gene 522:70-4, 2013. Pubmed reference: 23558247. DOI: 10.1016/j.gene.2013.03.084.

Edit History


  • Created by Frank Nicholas on 29 Jan 2014
  • Changed by Frank Nicholas on 29 Jan 2014