OMIA:000823-9793 : Prognathism in Equus asinus
Categories: Skeleton phene (incl. short stature & teeth)
Possibly relevant human trait(s) and/or gene(s) (MIM number): 176700 (trait)
Links to MONDO diseases: No links.
Mendelian trait/disorder: unknown
Considered a defect: yes
Cross-species summary: abnormal protrusion of the mandible
Markers: Using a comparative candidate gene strategy, based on evidence from humans, Rodrigues et al. (2013) identified a SNP (g503G>A) in an intron of the MATN1 gene (encoding Matrilin-1) with a significant association with this disorder.
Breed: Zamorano-Leonés-Spain, Spain (Ass) (VBO_0001829).
Cite this entry
|2013||Rodrigues, J.B., Araújo, S., Guedes-Pinto, H., San Roman, F., Viegas, C., Bastos, E. :|
|Analysis of new Matrilin-1 gene variants in a case-control study related to dental malocclusions in Equus asinus. Gene 522:70-4, 2013. Pubmed reference: 23558247 . DOI: 10.1016/j.gene.2013.03.084.|
- Changed by Frank Nicholas on 29 Jan 2014
- Created by Frank Nicholas on 29 Jan 2014