OMIA 001071-9940 : Wilson disease in Ovis aries |
In other species:
cattle
,
dog
,
pig
,
domestic cat
Possibly relevant human trait(s) and/or gene(s)s (MIM numbers):
277900 (trait)
,
606882 (gene)
Mendelian trait/disorder:
unknown
Considered a defect:
yes
Cross-species summary:
A disorder of copper metabolism, due to a deficiency of ceruloplasmin, which forms a complex with copper. The excess copper is deposited in the brain (causing mental retardation) or the liver (causing jaundice and cirrhosis).
References
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
2000 | Lockhart, P.J., Wilcox, S.A., Dahl, H.H.M., Mercer, J.F.B. : | |
Cloning, mapping and expression analysis of the sheep Wilson disease gene homologue Biochimica et Biophysica Acta - Gene Structure & Expression 1491:229-239, 2000. | ||
1987 | Howell, J.M., Wiener, G., Gawthorne, J.M. : | |
The genetics of copper metabolism in animals and man :45-61, 1987. |
Edit History
- Created by Frank Nicholas on 06 Sep 2005