OMIA 001071-9823 : Wilson disease in Sus scrofa

In other species: cattle , dog , sheep

Possibly relevant human trait(s) and/or gene(s) (MIM number): 277900

Mendelian trait/disorder: unknown

Considered a defect: yes

Cross-species summary: A disorder of copper metabolism, due to a deficiency of ceruloplasmin, which forms a complex with copper. The excess copper is deposited in the brain (causing mental retardation) or the liver (causing jaundice and cirrhosis).

Reference


1987 Howell, J.M., Wiener, G., Gawthorne, J.M. :
The genetics of copper metabolism in animals and man :45-61, 1987.

Edit History


  • Created by Frank Nicholas on 06 Sep 2005