OMIA 001360-9913 : Trimethylaminuria (fishy taint) in Bos taurus
|Symbol||Description||Species||Chr||Location||OMIA gene details page||Other Links|
|FMO3||flavin containing monooxygenase 3||Bos taurus||16||NC_037343.1 (38649500..38676494)||FMO3||Homologene, Ensembl, NCBI gene|
By default, variants are sorted chronologically by year of publication, to provide a historical perspective. Readers can re-sort on any column by clicking on the column header. Click it again to sort in a descending order. To create a multiple-field sort, hold down Shift while clicking on the second, third etc relevant column headers.
WARNING! Inclusion of a variant in this table does not automatically mean that it should be used for DNA testing. Anyone contemplating the use of any of these variants for DNA testing should examine critically the relevant evidence (especially in breeds other than the breed in which the variant was first described). If it is decided to proceed, the location and orientation of the variant sequence should be checked very carefully.
|Breed(s)||Variant Phenotype||Gene||Allele||Type of Variant||Reference Sequence||Chr.||g. or m.||c. or n.||p.||Verbal Description||EVA ID||Year Published||PubMed ID(s)||Acknowledgements|
|Swedish Red and White||Trimethylaminuria (fishy taint)||FMO3||nonsense (stop-gain)||UMD 3.1||16||g.39523051C>T||c.712C>T||p.R238*||rs797790546||2002||12466292||Variant coordinates obtained from or confirmed by EBI's Some Effect Predictor (VEP) tool; rsID gleaned from or confirmed by Table 1 of Â Sharma et al. (2017) Animal Genetics 48(3):369-370|
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
|2002||Lunden, A., Marklund, S., Gustafsson, V., Andersson, L. :|
|A nonsense mutation in the FMO3 gene underlies fishy off-flavor in cow's milk Genome Research 12:1885-1888, 2002. Pubmed reference: 12466292. DOI: 10.1101/gr.240202.|
|Lundén, A., Gustafsson, V., Imhof, M., Gauch, R., Bosset, J.O. :|
|High trimethylamine concentration in milk from cows on standard diets is expressed as fishy off-flavour. J Dairy Res 69:383-90, 2002. Pubmed reference: 12369409.|
- Created by Frank Nicholas on 10 Sep 2005
- Changed by Frank Nicholas on 09 Dec 2011
- Changed by Frank Nicholas on 21 Sep 2012
- Changed by Frank Nicholas on 30 Nov 2013