OMIA:001402-37607 : Multidrug resistance 1, ABCB1-related in Pyrrhula pyrrhula (Eurasian bullfinch)

In other species: dog , domestic cat , taurine cattle , goat

Categories: Homeostasis / metabolism phene

Links to possible relevant human trait(s) and/or gene(s) in OMIM: 171050 (gene) , 120080 (trait)

Single-gene trait/disorder: unknown

Disease-related: unknown

Cross-species summary: MDR1

Species summary: Heilmann et al. (2026) investigated the cause of suspected ivermectin hypersensitivity in the Eurasian bullfinch: "although a distinct genetic feature was identified in the ABCB1 linker region of some passerine birds, no functional differences in Rhodamine 123 efflux or inhibitor sensitivity were detected. [The authors] in vitro data do not support a role of this ABCB1 insertion for the suspected ivermectin hypersensitivity in the Eurasian bullfinch."

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Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2026). OMIA:001402-37607: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70

Reference

2026 Heilmann, K., Kempf, L.C., Siegl, L., Hamann, M., Lierz, M., Geyer, J. :
Cloning, structural and functional characterization of the ABCB1 transporter of the Eurasian bullfinch (Pyrrhula pyrrhula). Front Vet Sci 13:1759019, 2026. Pubmed reference: 42038050. DOI: 10.3389/fvets.2026.1759019.

Edit History


  • Created by Imke Tammen2 on 30 Apr 2026
  • Changed by Imke Tammen2 on 30 Apr 2026