OMIA:001943-9925 : Fecundity, generic in Capra hircus (goat)

In other species: dog , pig , taurine cattle , indicine cattle (zebu) , sheep

Categories: Reproductive system phene

Links to MONDO diseases: No links.

Mendelian trait/disorder: no

Mode of inheritance: Multifactorial

Considered a defect: no

Key variant known: no

Genetic engineering: Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing

Breeds: Jining Grey, China (Goat) (VBO_0009438), Shanbei White Cashmere, China (Goat) (VBO_0009450).
Breeds in which the phene has been documented. For breeds in which a likely causal variant has been documented, see the variant table below

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2021). OMIA:001943-9925: Online Mendelian Inheritance in Animals (OMIA) [dataset].


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2024 An, D., Chen, X., Li, Z., Dai, L., Huang, J., Xiao, M., Liu, H., Xu, J., Ruan, Y. :
Genetic variation in the BLM gene and its expression in the ovaries is closely related to kidding number in goats. Theriogenology 218:S0093-691X(24)00071-2:254-266, 2024. Pubmed reference: 38367334. DOI: 10.1016/j.theriogenology.2024.02.013.
2023 Bian, Z., Li, K., Chen, S., Man, C., Wang, F., Li, L. :
Association between INHA gene polymorphisms and litter size in Hainan black goats. PeerJ 11:e15381, 2023. Pubmed reference: 37187517. DOI: 10.7717/peerj.15381.
Fang, X., Gu, B., Chen, M., Sun, R., Zhang, J., Zhao, L., Zhao, Y. :
Genome-wide association study of the reproductive traits of the Dazu black goat (Capra hircus) using whole-genome resequencing. Genes (Basel) 14, 2023. Pubmed reference: 37895309. DOI: 10.3390/genes14101960.
Sahoo, S., Alex, R., Vohra, V., Mukherjee, S., Gowane, G.R. :
Estimation of genetic parameters and genetic change of first parity reproductive traits in Alpine × Beetal goats. Reprod Domest Anim , 2023. Pubmed reference: 37405572. DOI: 10.1111/rda.14418.
Sun, X., Niu, Q., Jiang, J., Wang, G., Zhou, P., Li, J., Chen, C., Liu, L., Xu, L., Ren, H. :
Identifying candidate genes for litter size and three morphological traits in Youzhou dark goats based on genome-wide SNP markers. Genes (Basel) 14, 2023. Pubmed reference: 37372363. DOI: 10.3390/genes14061183.
Wang, W., Wang, Y., Liu, Y., Cao, G., Di, R., Wang, J., Chu, M. :
Polymorphism and expression of GLUD1 in relation to reproductive performance in Jining Grey goats. Arch Anim Breed 66:411-419, 2023. Pubmed reference: 38205377. DOI: 10.5194/aab-66-411-2023.
Wijayanti, D., Luo, Y., Bai, Y., Pan, C., Qu, L., Guo, Z., Lan, X. :
New insight into copy number variations of goat SMAD2 gene and their associations with litter size and semen quality. Theriogenology 206:114-122, 2023. Pubmed reference: 37229957. DOI: 10.1016/j.theriogenology.2023.05.012.
Zhang, Y., Chen, X., Ruan, Y., Guo, W., Chen, J., Tang, W., Ji, Q., Fu, K. :
Effect of CTSS non-synonymous mutations on litter size in Qianbei Ma goats. Front Vet Sci 10:1276673, 2023. Pubmed reference: 38089704. DOI: 10.3389/fvets.2023.1276673.
Zhou, A., Ding, Y., Zhang, X., Zhou, Y., Liu, Y., Li, T., Xiao, L. :
Whole-genome resequencing reveals new mutations in candidate genes for Beichuan-white goat prolificacya. Anim Biotechnol :1-12, 2023. Pubmed reference: 37729465. DOI: 10.1080/10495398.2023.2258166.
2021 Bai, Y., Li, J., Zhu, H., Liu, J., Dong, S., Li, L., Qu, L., Chen, H., Song, X., Lan, X. :
Deletion mutation within the goat PPP3CA gene identified by GWAS significantly affects litter size. Reprod Fertil Dev 33:476-483, 2021. Pubmed reference: 33883061. DOI: 10.1071/RD20337.
Yang, Y., Sun, X., Cui, W., Liu, N., Wang, K., Qu, L., Pan, C. :
The detection of mutation within goat cell division cycle 25 A and its effect on kidding number. Anim Biotechnol :1-6, 2021. Pubmed reference: 33879023. DOI: 10.1080/10495398.2021.1910519.
Zhang, X., Yuan, R., Bai, Y., Yang, Y., Song, X., Lan, X., Pan, C. :
A deletion mutation within the goat AKAP13 gene is significantly associated with litter size. Anim Biotechnol :1-7, 2021. Pubmed reference: 34431749. DOI: 10.1080/10495398.2021.1968418.
2020 Hui, Y., Zhang, Y., Wang, K., Pan, C., Chen, H., Qu, L., Song, X., Lan, X. :
Goat DNMT3B: An indel mutation detection, association analysis with litter size and mRNA expression in gonads. Theriogenology 147:108-115, 2020. Pubmed reference: 32122684. DOI: 10.1016/j.theriogenology.2020.02.025.
2019 Chen, M., Yan, H., Wang, K., Cui, Y., Chen, R., Liu, J., Zhu, H., Qu, L., Pan, C. :
Goat SPEF2: Expression profile, indel variants identification and association analysis with litter size. Theriogenology 139:147-155, 2019. Pubmed reference: 31408832. DOI: 10.1016/j.theriogenology.2019.08.007.
Kang, Z., Zhang, S., He, L., Zhu, H., Wang, Z., Yan, H., Huang, Y., Dang, R., Lei, C., Chen, H., Qu, L., Lan, X., Pan, C. :
A 14-bp functional deletion within the CMTM2 gene is significantly associated with litter size in goat. Theriogenology 139:49-57, 2019. Pubmed reference: 31362196. DOI: 10.1016/j.theriogenology.2019.07.026.
Zhang, Y., Cui, W., Yang, H., Wang, M., Yan, H., Zhu, H., Liu, J., Qu, L., Lan, X., Pan, C. :
A novel missense mutation (L280V) within POU1F1 gene strongly affects litter size and growth traits in goat. Theriogenology 135:198-203, 2019. Pubmed reference: 31226610. DOI: 10.1016/j.theriogenology.2019.06.021.
2018 Su, F., Guo, X., Wang, Y., Wang, Y., Cao, G., Jiang, Y. :
Genome-wide analysis on the landscape of transcriptomes and their relationship with DNA methylomes in the hypothalamus reveals genes related to sexual precocity in Jining gray goats. Front Endocrinol (Lausanne) 9:501, 2018. Pubmed reference: 30214427. DOI: 10.3389/fendo.2018.00501.
Wang, K., Yan, H., Xu, H., Yang, Q., Zhang, S., Pan, C., Chen, H., Zhu, H., Liu, J., Qu, L., Lan, X. :
A novel indel within goat casein alpha S1 gene is significantly associated with litter size. Gene 671:161-169, 2018. Pubmed reference: 29864495. DOI: 10.1016/j.gene.2018.05.119.

Edit History

  • Created by Frank Nicholas on 31 Oct 2016
  • Changed by Imke Tammen2 on 25 Jun 2021
  • Changed by Imke Tammen2 on 14 Aug 2021
  • Changed by Imke Tammen2 on 28 Aug 2021