OMIA:002328-8090 : Behaviour in Oryzias latipes (Japanese medaka)

In other species: rainbow trout , chicken , Great Tit , white-tufted-ear marmoset , Rhesus monkey , Yellow baboon , hamadryas baboon , pygmy chimpanzee , chimpanzee , dog , domestic cat , horse , pig , taurine cattle , indicine cattle (zebu) , goat , sheep , rabbit , deer mice , blackcap , Swainson's thrush , Guinea baboon , Tibetan ground-tit , burrowing owl , Australian zebra finch

Categories: Behaviour / neurological phene

Mendelian trait/disorder: unknown

Considered a defect: no

Species-specific description: Lu et al. (2023) "established a sws2a and sws2b knockout medaka model by CRISPR/Cas9 technology. We discovered that medaka sws2a and sws2b are mainly expressed in the eyes and may be regulated by growth differentiation factor 6a (gdf6a). Compared with the WT, sws2a-/- and sws2b-/- mutant larvae displayed an increase in swimming speed during the changes from light to dark ... . " (GMO) Seki et al. (2023) "used the CRISPR/Cas9-mediated knock-in approach to establish a transgenic medaka strain expressing the Chloromonas oogama channelrhodopsin (CoChR) in the ISL LIM homeobox 1 (isl1) locus. We demonstrated that light stimuli elicited specific behavioral responses such as bending or turning locomotion in the embryos and pectoral fin movements in the larvae and adults." (GMO)

Genetic engineering: Yes - in addition to the occurrence of natural variants, variants have been created artificially, e.g. by genetic engineering or gene editing
Have human generated variants been created, e.g. through genetic engineering and gene editing

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2023). OMIA:002328-8090: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70

References

Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2023 Lu, K., Wu, J., Tang, S., Jia, X., Liang, X.F. :
Knockout of sws2a and sws2b in medaka (Oryzias latipes) reveals their roles in regulating vision-guided behavior and eye development. Int J Mol Sci 24:8786, 2023. Pubmed reference: 37240129. DOI: 10.3390/ijms24108786.
Nakayama, T., Hirano, F., Okushi, Y., Matsuura, K., Ohashi, M., Matsumiya, A., Yoshimura, T. :
Orphan nuclear receptor nr4a1 regulates winter depression-like behavior in medaka. Neurosci Lett :137469, 2023. Pubmed reference: 37669713. DOI: 10.1016/j.neulet.2023.137469.
Seki, T., Takeuchi, H., Ansai, S. :
Optogenetic control of medaka behavior with channelrhodopsin. Dev Growth Differ 65:288-299, 2023. Pubmed reference: 37354208. DOI: 10.1111/dgd.12872.

Edit History


  • Created by Imke Tammen2 on 30 May 2023
  • Changed by Imke Tammen2 on 26 Jun 2023
  • Changed by Imke Tammen2 on 15 Oct 2023
  • Changed by Imke Tammen2 on 18 Dec 2023