OMIA:002328-9615 : Behaviour in Canis lupus familiaris (dog)

In other species: rainbow trout , Japanese medaka , chicken , Great Tit , white-tufted-ear marmoset , Rhesus monkey , Yellow baboon , hamadryas baboon , pygmy chimpanzee , chimpanzee , domestic cat , horse , pig , taurine cattle , indicine cattle (zebu) , goat , sheep , rabbit , deer mice , blackcap , Guinea baboon , Tibetan ground-tit , burrowing owl , Australian zebra finch

Categories: Behaviour / neurological phene

Links to MONDO diseases: No links.

Mendelian trait/disorder: no

Mode of inheritance: Multifactorial

Considered a defect: unknown

Key variant known: no

Genetic engineering: Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing

Breeds: Belgian Shepherd Dog, Malinois (Dog) (VBO_0200147), German Shepherd Dog (Dog) (VBO_0200577).
Breeds in which the phene has been documented. For breeds in which a likely causal variant has been documented, see the variant table below

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2021). OMIA:002328-9615: Online Mendelian Inheritance in Animals (OMIA) [dataset].


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2024 Csibra, B., Bunford, N., Gácsi, M. :
Development of a human-analogue, 3-symptom domain Dog ADHD and Functionality Rating Scale (DAFRS). Sci Rep 14:1808, 2024. Pubmed reference: 38245569. DOI: 10.1038/s41598-024-51924-9.
Fallahi, M., Masoudi, A.A., Torshizi, R.V. :
Genetic variants in the TAC1 transcriptional regulatory region affect on trainability and excitability levels in Belgian Malinois dogs. Vet Med Sci 10:e1346, 2024. Pubmed reference: 38227710. DOI: 10.1002/vms3.1346.
2023 Bai, J., Chen, S., Zhou, Z., Zhao, X., Song, M., Wang, F., Wang, J. :
Association between TH/MAOB gene single nucleotide polymorphisms and excitability in Labrador Retrievers. Anim Genet , 2023. Pubmed reference: 37185969. DOI: 10.1111/age.13326.
Engdahl, K.S., Brodbelt, D.C., Cameron, C., Church, D.B., Hedhammar, Å., O'Neill, D.G. :
Demography and disorders of English Cocker Spaniels under primary veterinary care in the UK. Canine Med Genet 10:4, 2023. Pubmed reference: 37202773. DOI: 10.1186/s40575-023-00128-x.
Eyre, A.W., Zapata, I., Hare, E., Serpell, J.A., Otto, C.M., Alvarez, C.E. :
Machine learning prediction and classification of behavioral selection in a canine olfactory detection program. Sci Rep 13:12489, 2023. Pubmed reference: 37528118. DOI: 10.1038/s41598-023-39112-7.
Gnanadesikan, G.E., Tandon, D., Bray, E.E., Kennedy, B.S., Tennenbaum, S.R., MacLean, E.L., vonHoldt, B.M. :
Transposons in the Williams-Beuren syndrome critical region are associated with social behavior in assistance dogs. Behav Genet , 2023. Pubmed reference: 38091228. DOI: 10.1007/s10519-023-10166-7.
Handegård, K.W., Storengen, L.M., Joergensen, D., Lingaas, F. :
Genomic analysis of firework fear and noise reactivity in standard poodles. Canine Med Genet 10:2, 2023. Pubmed reference: 36890545. DOI: 10.1186/s40575-023-00125-0.
Matsumoto, Y., Konno, A., Ishihara, G., Inoue-Murayama, M. :
Genetic dissection of behavioral traits related to successful training of drug detection dogs. Sci Rep 13:7326, 2023. Pubmed reference: 37147374. DOI: 10.1038/s41598-023-33638-6.
Morrill, K., Chen, F., Karlsson, E. :
Comparative neurogenetics of dog behavior complements efforts towards human neuropsychiatric genetics. Hum Genet , 2023. Pubmed reference: 37578529. DOI: 10.1007/s00439-023-02580-y.
Salonen, M., Mikkola, S., Niskanen, J.E., Hakanen, E., Sulkama, S., Puurunen, J., Lohi, H. :
Breed, age, and social environment are associated with personality traits in dogs. iScience 26:106691, 2023. Pubmed reference: 37168553. DOI: 10.1016/j.isci.2023.106691.
Webb, M., Thwaites, B., Mullineaux, E., Calder, C., Waddon, V., Hayes, E., Gaines, S., Flynn, M. :
Dog behaviour influenced by more than genetics. Vet Rec 193:415-416, 2023. Pubmed reference: 37975441. DOI: 10.1002/vetr.3697.
2019 Friedrich, J., Strandberg, E., Arvelius, P., Sánchez-Molano, E., Pong-Wong, R., Hickey, J.M., Haskell, M.J., Wiener, P. :
Genetic dissection of complex behaviour traits in German Shepherd dogs. Heredity (Edinb) 123:746-758, 2019. Pubmed reference: 31611599. DOI: 10.1038/s41437-019-0275-2.
Tandon, D., Ressler, K., Petticord, D., Papa, A., Jiranek, J., Wilkinson, R., Kartzinel, R.Y., Ostrander, E.A., Burney, N., Borden, C., Udell, M.A.R., VonHoldt, B.M. :
Homozygosity for mobile element insertions associated with WBSCR17 could predict success in assistance dog training programs. Genes (Basel) 10, 2019. Pubmed reference: 31181852. DOI: 10.3390/genes10060439.
2013 Lit, L., Belanger, J.M., Boehm, D., Lybarger, N., Oberbauer, A.M. :
Differences in behavior and activity associated with a poly(a) expansion in the dopamine transporter in Belgian Malinois. PLoS One 8:e82948, 2013. Pubmed reference: 24376613. DOI: 10.1371/journal.pone.0082948.
Lit, L., Belanger, J.M., Boehm, D., Lybarger, N., Haverbeke, A., Diederich, C., Oberbauer, A.M. :
Characterization of a dopamine transporter polymorphism and behavior in Belgian Malinois. BMC Genet 14:45, 2013. Pubmed reference: 23718893. DOI: 10.1186/1471-2156-14-45.

Edit History

  • Created by Imke Tammen2 on 20 Apr 2021
  • Changed by Imke Tammen2 on 20 Apr 2021
  • Changed by Imke Tammen2 on 18 Oct 2021