OMIA:002771 : Lissencephaly, generic |
Categories: Nervous system phene
Cross-species summary: Lissencephalic brains (brains with a smooth cerebral cortex) are normal in many species (including some small rodents and small primates). The disease lissencephaly refers to a group of brain conditions in species that normally have gyrencephalic brains, in which the cerebral cortex is smooth due to defective neuronal migration during embryonic development resulting in a reduction or absence of sulci and gyri. Various non-genetic and genetic factors have been reported to cause lissencephaly.
Species in which this phene is found:
dog (Canis lupus familiaris)
domestic cat (Felis catus)
taurine cattle (Bos taurus)
goat (Capra hircus)
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- Created by Imke Tammen2 on 22 Sep 2023