OMIA:002771-9925 : Lissencephaly, generic in Capra hircus (goat)

In other species: dog , domestic cat , taurine cattle

Categories: Nervous system phene

Mendelian trait/disorder: unknown

Considered a defect: yes

Cross-species summary: Lissencephalic brains (brains with a smooth cerebral cortex) are normal in many species (including some small rodents and small primates). The disease lissencephaly refers to a group of brain conditions in species that normally have gyrencephalic brains, in which the cerebral cortex is smooth due to defective neuronal migration during embryonic development resulting in a reduction or absence of sulci and gyri. Various non-genetic and genetic factors have been reported to cause lissencephaly.

Species-specific description: Some references listed here were previously listed under OMIA:001867

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2023). OMIA:002771-9925: Online Mendelian Inheritance in Animals (OMIA) [dataset].


2013 Santos, J.R.S. dos, Dantas, A.F.M., Pessoa, C.R.M., Silva, T.R., Simões, S.V.D., Riet-Correa, F., Pedrosa, D. :
Lisencefalia e hipoplasia cerebelar em caprino [Lissencephaly and cerebellar hypoplasia in a goat] Cienc. Rural 43:1858-1961, 2013. DOI:

Edit History

  • Created by Imke Tammen2 on 22 Sep 2023