OMIA:002771-9913 : Lissencephaly, generic in Bos taurus (taurine cattle)
Categories: Nervous system phene
Links to MONDO diseases: No links.
Mendelian trait/disorder: unknown
Considered a defect: yes
Cross-species summary: Lissencephalic brains (brains with a smooth cerebral cortex) are normal in many species (including some small rodents and small primates). The disease lissencephaly refers to a group of brain conditions in species that normally have gyrencephalic brains, in which the cerebral cortex is smooth due to defective neuronal migration during embryonic development resulting in a reduction or absence of sulci and gyri. Various non-genetic and genetic factors have been reported to cause lissencephaly.
Species-specific description: Some references listed here were previously listed under OMIA:001867
Have human generated variants been created, e.g. through genetic engineering and gene editing
Cite this entry
|2016||Santos, B.L.dos, Damé, M.C.F., Coelho, A.C.B., Oliveira, P.A., Marcolongo-Pereira, C., Schild, A.L. :|
|Lisencefalia-paquigiria e hipoplasia cerebelar em um bovino [Lissencephaly-pachygyria and cerebellar hypoplasia in a calf]. Cienc. Rural 46:1622-1628, 2016. DOI: doi.org/10.1590/0103-8478cr20151572.|
- Created by Imke Tammen2 on 22 Sep 2023