Gene PRNP : prion protein in Bos taurus

See the equivalent entry at NCBI

In other species: Norway rat , sheep , horse , goat , water buffalo , white-tailed deer , Bank vole

Symbol: PRNP

Synonyms: AltPrP, PrP

Description: prion protein

Type of gene: protein-coding

NCBI gene id: 281427

Other designations: major prion protein|alternative prion protein|major scrapie-associated fibril protein 1|prion protein (p27-30) (Creutzfeldt-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia)|prion protein PrP|prion protein precursor PrP

Links: Homologene , Ensembl

Genomic location: 13:47039937..47060168 [Chromosome accession NC_037340.1]

Related phenes:

OMIA:000944-9913 : Spongiform encephalopathy, susceptibility/resistance to in Bos taurus


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
2015 Choi, W., Kim, E., Yum, S.Y., Lee, C., Lee, J., Moon, J., Ramachandra, S., Malaweera, B.O., Cho, J., Kim, J.S., Kim, S., Jang, G. :
Efficient PRNP deletion in bovine genome using gene-editing technologies in bovine cells. Prion 9:278-91, 2015. Pubmed reference: 26217959. DOI: 10.1080/19336896.2015.1071459.
2014 Uchida, L., Heriyanto, A., Thongchai, C., Hanh, T.T., Horiuchi, M., Ishihara, K., Tamura, Y., Muramatsu, Y. :
Genetic diversity in the prion protein gene (PRNP) of domestic cattle and water buffaloes in Vietnam, Indonesia and Thailand. J Vet Med Sci 76:1001-8, 2014. Pubmed reference: 24705506.
2005 Abrial, D., Calavas, D., Jarrige, N., Ducrot, C. :
Spatial heterogeneity of the risk of BSE in France following the ban of meat and bone meal in cattle feed. Prev Vet Med 67:69-82, 2005.
Baron, T., Calavas, D. :
[Bovine spongiform encephalopathy] Pathol Biol (Paris) 53:229-36, 2005. Pubmed reference: 15850957. DOI: 10.1016/j.patbio.2004.09.009.
2004 Bailly, Y., Haeberlé, A.M., Blanquet-Grossard, F., Chasserot-Golaz, S., Grant, N., Schulze, T., Bombarde, G., Grassi, J., Cesbron, J.Y., Lemaire-Vieille, C. :
Prion protein (PrPc) immunocytochemistry and expression of the green fluorescent protein reporter gene under control of the bovine PrP gene promoter in the mouse brain. J Comp Neurol 473:244-69, 2004. Pubmed reference: 15101092. DOI: 10.1002/cne.20117.
O'Rourke, K. :
O.I.E. takes action at annual meeting. Agency acts on measures involving BSE, zoonoses, animal welfare, and the disease notification system. J Am Vet Med Assoc 225:486-7, 2004.
Seabury, CM., Honeycutt, RL., Rooney, AP., Halbert, ND., Derr, JN. :
Prion protein gene (PRNP) variants and evidence for strong purifying selection in functionally important regions of bovine exon 3. Proc Natl Acad Sci U S A 101:15142-7, 2004.
1998 Iannuzzi, L., Palomba, R., Dimeo, G.P., Perucatti, A., Ferrara, L. :
Comparative FISH-mapping of the prion protein gene (PrnP) on cattle, river buffalo, sheep and goat chromosomes Cytogenetics & Cell Genetics 81:202-204, 1998.
1993 Prusiner, S.B., Fuzi, M., Scott, M., Serban, D., Serban, H., Taraboulos, A., Gabriel, J.M., Wells, G.A.H., Wilesmith, J.W., Bradley, R., Dearmond, S.J., Kristensson, K. :
Immunologic and Molecular Biologic Studies of Prion Proteins in Bovine Spongiform Encephalopathy Journal of Infectious Diseases 167:602-613, 1993. Pubmed reference: 8440932.
1992 Yoshimoto, J., Iinuma, T., Ishiguro, N., Horiuchi, M., Imamura, M., Shinagawa, M. :
Comparative Sequence Analysis and Expression of Bovine PrP Gene in Mouse L-929 Cells Virus Genes 6:343-356, 1992. Pubmed reference: 1362024.