OMIA 000240-8932 : Crest in Columba livia |
In other species:
chicken
,
,
budgerigar
,
ringneck dove
Mendelian trait/disorder:
yes
Mode of inheritance:
Autosomal Recessive
Considered a defect:
no
Key variant known:
yes
Year key variant first reported:
2013
Cross-species summary:
Also called feather-crested head.
Species-specific description:
As summarised by Vickrey et al. (2015), "the head crest of domestic pigeons is a recessive phenotype characterized by reversed polarity of the neck and occipital feathers, causing the feathers to grow in a cranial rather than caudal direction".
Molecular basis:
In the words of Vickrey et al. (2016), Shapiro et al. (2013) reported "a single amino acid substitution (Arg758Cys) in the active site of the kinase domain of Ephrin receptor B2".
Associated gene:
| Symbol | Description | Species | Chr | Location | OMIA gene details page | Other Links |
|---|---|---|---|---|---|---|
| EPHB2 | EPH receptor B2 | Columba livia | - | no genomic information (-..-) | EPHB2 | Homologene, Ensembl, NCBI gene |
Variants
By default, variants are sorted chronologically by year of publication, to provide a historical perspective.
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| Breed(s) | Variant Phenotype | Gene | Allele | Type of Variant | Reference Sequence | Chr. | g. or m. | c. or n. | p. | Verbal Description | EVA ID | Year Published | PubMed ID(s) | Acknowledgements |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Crest | EPHB2 | missense | p.R758C | 2013 | 23371554 |
References
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
| 2015 | Caspermeyer, J. : | |
| Birds of a Feather: Pigeon Head Crest Findings Extend to Domesticated Doves. Mol Biol Evol 32:2801, 2015. Pubmed reference: 26285654. DOI: 10.1093/molbev/msv162. | ||
| Vickrey, A.I., Domyan, E.T., Horvath, M.P., Shapiro, M.D. : | ||
| Convergent Evolution of Head Crests in Two Domesticated Columbids Is Associated with Different Missense Mutations in EphB2. Mol Biol Evol 32:2657-64, 2015. Pubmed reference: 26104009. DOI: 10.1093/molbev/msv140. | ||
| 2013 | Shapiro, M.D., Kronenberg, Z., Li, C., Domyan, E.T., Pan, H., Campbell, M., Tan, H., Huff, C.D., Hu, H., Vickrey, A.I., Nielsen, S.C., Stringham, S.A., Hu, H., Willerslev, E., Gilbert, M.T., Yandell, M., Zhang, G., Wang, J. : | |
| Genomic diversity and evolution of the head crest in the rock pigeon. Science 339:1063-7, 2013. Pubmed reference: 23371554. DOI: 10.1126/science.1230422. |
Edit History
- Created by Frank Nicholas on 05 Aug 2016
- Changed by Frank Nicholas on 05 Aug 2016