OMIA 000478-9823 : Holoprosencephaly in Sus scrofa

In other species: domestic cat , horse , sheep

Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 236100 , 157170 , 142945 , 142946 , 609637 , 605934 , 610828 , 609408 , 610829 , 614226

Mendelian trait/disorder: unknown

Considered a defect: yes

Cross-species summary: Developmental failure of cleavage of the forebrain (prosencephalon); with a deficit in midline facial development, and with cyclopia (see MIA 000249) in the severe form.

Inheritance: There are no data available on inheritance.

Reference


1989 Fisher, K.R.S., Partlow, G.D., Holmes, C.J. :
Anatomical Observations of Holoprosencephaly in Swine Journal of Craniofacial Genetics and Developmental Biology 9:135-146, 1989. Pubmed reference: 2794004.

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  • Created by Frank Nicholas on 06 Sep 2005