OMIA:000478-9823 : Holoprosencephaly in Sus scrofa (pig) |
In other species: domestic cat , horse , sheep
Categories: Craniofacial phene
Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 236100 (trait) , 157170 (trait) , 142945 (trait) , 142946 (trait) , 609637 (trait) , 605934 (trait) , 610828 (trait) , 609408 (trait) , 610829 (trait) , 614226 (trait)
Links to MONDO diseases: No links.
Mendelian trait/disorder: unknown
Considered a defect: yes
Cross-species summary: Developmental failure of cleavage of the forebrain (prosencephalon); with a deficit in midline facial development, and with cyclopia (see MIA 000249) in the severe form.
Inheritance: There are no data available on inheritance.
Genetic engineering:
Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing
Cite this entry
Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2005). OMIA:000478-9823: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70
Reference
| 1989 | Fisher, K.R.S., Partlow, G.D., Holmes, C.J. : |
| Anatomical Observations of Holoprosencephaly in Swine Journal of Craniofacial Genetics and Developmental Biology 9:135-146, 1989. Pubmed reference: 2794004. |
Edit History
- Created by Frank Nicholas on 06 Sep 2005