OMIA:000478-9823 : Holoprosencephaly in Sus scrofa (pig)
Categories: Craniofacial phene
Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 236100 (trait) , 157170 (trait) , 142945 (trait) , 142946 (trait) , 609637 (trait) , 605934 (trait) , 610828 (trait) , 609408 (trait) , 610829 (trait) , 614226 (trait)
Links to MONDO diseases: No links.
Mendelian trait/disorder: unknown
Considered a defect: yes
Cross-species summary: Developmental failure of cleavage of the forebrain (prosencephalon); with a deficit in midline facial development, and with cyclopia (see MIA 000249) in the severe form.
Inheritance: There are no data available on inheritance.
Have human generated variants been created, e.g. through genetic engineering and gene editing
Cite this entry
|1989||Fisher, K.R.S., Partlow, G.D., Holmes, C.J. :|
|Anatomical Observations of Holoprosencephaly in Swine Journal of Craniofacial Genetics and Developmental Biology 9:135-146, 1989. Pubmed reference: 2794004.|
- Created by Frank Nicholas on 06 Sep 2005