OMIA 000478-9940 : Holoprosencephaly in Ovis aries

In other species: pig , horse , domestic cat

Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 236100 , 157170 , 142945 , 142946 , 609637 , 605934 , 610828 , 609408 , 610829 , 614226

Mendelian trait/disorder: unknown

Considered a defect: yes

Cross-species summary: Developmental failure of cleavage of the forebrain (prosencephalon); with a deficit in midline facial development, and with cyclopia (see MIA 000249) in the severe form.

Species-specific name: Congenital holoprosencephaly

References


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
2008 Zeiss, CJ., Zarfoss, MK., Johnson, EE., Dubielzig, RR. :
Ocular anomalies and holoprosencephaly in a lamb. Vet Ophthalmol 11:30-3, 2008. Pubmed reference: 18190349. DOI: 10.1111/j.1463-5224.2007.00597.x.
1987 Roth, IJ., Morrow, CJ., Wilkins, JF., Harper, PA. :
Holoprosencephaly in Border Leicester lambs. Aust Vet J 64:271-3, 1987. Pubmed reference: 3426465.

Edit History


  • Created by Frank Nicholas on 12 May 2010