Categories: Endocrine / exocrine gland phene (incl mammary gland)

Possible human homologues (MIM numbers): 240200 (trait) , 240300 (trait)

Cross-species summary: Hypoadrenocorticism, or Addison’s disease, results from insufficient secretion of steroid hormones (glucocorticoids and mineralocorticoids) from the adrenal glands. In primary hypoadrenocorticism the disease is due to changes to the adrenal cortex, while secondary hypoadrenocorticism refers to deficiency of ACTH, produced in the pituitary gland. The disease can be further classified as typical (glucocorticoid and mineralocorticoid deficiency) with typical electrolyte changes or atypical (only glucocorticoid deficiency with no typical electrolyte changes). The atypical cases often progress to become typical.

Species in which this phene is found:
dog (Canis lupus familiaris)
domestic cat (Felis catus)
horse (Equus caballus)
goat (Capra hircus)