OMIA 001216-9913 : Coat colour, roan in Bos taurus
|Symbol||Description||Species||Chr||Location||OMIA gene details page||Other Links|
|KITLG||KIT ligand||Bos taurus||5||NC_037332.1 (18311647..18251955)||KITLG||Homologene, Ensembl, NCBI gene|
By default, variants are sorted chronologically by year of publication, to provide a historical perspective. Readers can re-sort on any column by clicking on the column header. Click it again to sort in a descending order. To create a multiple-field sort, hold down Shift while clicking on the second, third etc relevant column headers.
WARNING! Inclusion of a variant in this table does not automatically mean that it should be used for DNA testing. Anyone contemplating the use of any of these variants for DNA testing should examine critically the relevant evidence (especially in breeds other than the breed in which the variant was first described). If it is decided to proceed, the location and orientation of the variant sequence should be checked very carefully.
Since October 2021, OMIA includes a semiautomated lift-over pipeline to facilitate updates of genomic positions to a recent reference genome position. These changes to genomic positions are not always reflected in the ‘acknowledgements’ or ‘verbal description’ fields in this table.
|OMIA Variant ID||Breed(s)||Variant Phenotype||Gene||Allele||Type of Variant||Source of Genetic Variant||Reference Sequence||Chr.||g. or m.||c. or n.||p.||Verbal Description||EVA ID||Inferred EVA rsID||Year Published||PubMed ID(s)||Acknowledgements|
|186||Belgian Blue Shorthorn||Roan||KITLG||missense||Naturally occurring variant||ARS-UCD1.2||5||g.18273206G>T||c.572C>A||p.(A191N)||1999||10384045||Variant information kindly provided or confirmed by Hubert Pausch, including information from Additional Table 6 of Jansen et al. (2013) BMC Genomics201314:446 https://doi.org/10.1186/1471-2164-14-446|
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
|2021||Derks, M.F.L., Steensma, M. :|
|Review: Balancing selection for deleterious alleles in livestock. Front Genet 12:761728, 2021. Pubmed reference: 34925454. DOI: 10.3389/fgene.2021.761728.|
|2000||Aasland, M., Klungland, H., Lien, S. :|
|Two polymorphisms in the bovine mast cell growth factor gene (MGF). Anim Genet 31:345, 2000. Pubmed reference: 11105228.|
|1999||Seitz, J.J., Schmutz, S.M., Thue, T.D., Buchanan, F.C. :|
|A missense mutation in the bovine MGF gene is associated with the roan phenotype in Belgian Blue and Shorthorn cattle Mammalian Genome 10:710-712, 1999. Pubmed reference: 10384045.|
|1996||Charlier, C., Denys, B., Belanche, J.I., Coppieters, W., Grobet, L., Mni, M., Womack, J., Hanset, R., Georges, M. :|
|Microsatellite mapping of the bovine roan locus - a major determinant of white heifer disease Mammalian Genome 7:138-142, 1996. Pubmed reference: 8835531.|
|1947||Jones, I.C. :|
|The inheritance of red, roan and white coat colour in dairy shorthorn cattle. J Genet 48:155-63, 1947. Pubmed reference: 20266729.|
|1909||Bateson, W. :|
|Mendel’s Principles of Heredity. Cambridge University Press, London :, 1909.|
- Created by Mohammad Shariflou on 10 Nov 2006
- Changed by Frank Nicholas on 09 Dec 2011
- Changed by Frank Nicholas on 15 Sep 2012