OMIA:002630-461245 : Tolerance to batrachotoxin (BTX) in Ifrita kowaldi (blue-capped ifrita) |
In other species: poison dart frogs , regent whistler , hooded pitohui , rufous-naped whistler , rusty pitohui , black pitohui
Categories: Nervous system phene , Muscle phene
Links to MONDO diseases: No links.
Mendelian trait/disorder: unknown
Considered a defect: no
Cross-species summary: Batrachotoxin (BTX) is a cardio- and neurotoxic steroidal alkaloid found in beetles, birds and frogs. BTX binds to voltage-gated sodium ion channels (coded for by SCN genes), leading to muscle paralysis and death. Several species of animals with a tolerance or auto-resistance to BTX, acquire BTX in their diet and transport BTX to their skin and/or feathers as a defence mechanism or possible parasite deterrence.
Genetic engineering:
Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing
Cite this entry
Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2023). OMIA:002630-461245: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70
Reference
| 2000 | Dumbacher, J.P., Spande, T.F., Daly, J.W. : |
| Batrachotoxin alkaloids from passerine birds: a second toxic bird genus (Ifrita kowaldi) from New Guinea. Proc Natl Acad Sci U S A 97:12970-5, 2000. Pubmed reference: 11035772. DOI: 10.1073/pnas.200346897. |
Edit History
- Created by Imke Tammen2 on 17 Feb 2023