OMIA:002630-461245 : Tolerance to batrachotoxin (BTX) in Ifrita kowaldi (blue-capped ifrita)

In other species: poison dart frogs , regent whistler , hooded pitohui , rufous-naped whistler , rusty pitohui , black pitohui

Categories: Nervous system phene , Muscle phene

Mendelian trait/disorder: unknown

Considered a defect: no

Cross-species summary: Batrachotoxin (BTX) is a cardio- and neurotoxic steroidal alkaloid found in beetles, birds and frogs. BTX binds to voltage-gated sodium ion channels (coded for by SCN genes), leading to muscle paralysis and death. Several species of animals with a tolerance or auto-resistance to BTX, acquire BTX in their diet and transport BTX to their skin and/or feathers as a defence mechanism or possible parasite deterrence.

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2023). OMIA:002630-461245: Online Mendelian Inheritance in Animals (OMIA) [dataset].


2000 Dumbacher, J.P., Spande, T.F., Daly, J.W. :
Batrachotoxin alkaloids from passerine birds: a second toxic bird genus (Ifrita kowaldi) from New Guinea. Proc Natl Acad Sci U S A 97:12970-5, 2000. Pubmed reference: 11035772. DOI: 10.1073/pnas.200346897.

Edit History

  • Created by Imke Tammen2 on 17 Feb 2023