Categories: Nervous system phene

Links to MONDO diseases: No links.

Cross-species summary: Lissencephalic brains (brains with a smooth cerebral cortex) are normal in many species (including some small rodents and small primates). The disease lissencephaly refers to a group of brain conditions in species that normally have gyrencephalic brains, in which the cerebral cortex is smooth due to defective neuronal migration during embryonic development resulting in a reduction or absence of sulci and gyri. Various non-genetic and genetic factors have been reported to cause lissencephaly.

Species in which this phene is found:
dog (Canis lupus familiaris)
domestic cat (Felis catus)
taurine cattle (Bos taurus)
goat (Capra hircus)