OMIA:000392-89462 : Chromosomal structural anomaly, fragile site, autosomal in Bubalus bubalis (water buffalo) |
In other species: dog , domestic cat , domestic horse , pig , taurine cattle , goat , sheep , rabbit , raccoon dog
Categories: Chromosomal phene
Links to possible relevant human trait(s) and/or gene(s) in OMIM: 136540 (trait) , 616109 (gene) , 136570 (trait) , 136580 (trait) , 136590 (trait) , 601464 (gene) , 136620 (trait) , 136640 (trait) , 601153 (gene) , 136660 (trait) , 600651 (trait) , 601153 (gene)
Single-gene trait/disorder: unknown
Disease-related: unknown
Cross-species summary: A site on a chromosome that does not stain, at which a break in the chromosome often occurs. In cultured cells, chromosomal breakage at fragile sites can be induced by the addition of caffeine or aphidicolon or bromodeoxyuridine to the culture medium. In humans, fragile sites are sometimes associated with tandem repeats of three nucleotides (triplet microsatellites) which, if the number of repeats increases, can cause inherited disorders. No such examples have yet been documented in domesticated animals.
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Cite this entry
Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2025). OMIA:000392-89462: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70
Reference
| 1998 | Pires, R.M.L., Reichert, R.H., Kasahara, S. : |
| Cytogenetics of three breeds of river buffalo (bubalus bubalis l.), with evidence of a fragile site on the X chromosome Theriogenology 49:529-538, 1998. Pubmed reference: 10732032. |
Edit History
- Created by Frank Nicholas on 17 Sep 2025