OMIA:000424-9615 : Goitre, familial in Canis lupus familiaris (dog)

In other species: chicken , American black bear , domestic cat , pig , taurine cattle , goat , sheep , golden hamster , bongo , water buffalo

Categories: Endocrine / exocrine gland phene (incl mammary gland)

Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 274700 (trait) , 188450 (gene)

Links to MONDO diseases:

Mendelian trait/disorder: unknown

Considered a defect: yes

Cross-species summary: Goitre is the enlargement of the thyroid gland, causing a swelling in the front of the neck. The condition can develop due to nutritional iodine deficiencies but familial forms of this disorder have been identified in several species. The molecular basis been determined for familial goitre in cattle and goats. Also spelt goiter.

Genetic engineering: Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2005). OMIA:000424-9615: Online Mendelian Inheritance in Animals (OMIA) [dataset].


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2012 Kuczynski, L.A., Schwartz, P., Peddle, G., Huang, S., Mai, W., Giger, U. :
Goiter with vascular anomalies in a litter of Polish Lowland sheepdogs. J Am Anim Hosp Assoc 48:278-83, 2012. Pubmed reference: 22611215. DOI: 10.5326/JAAHA-MS-5769.
1989 Verschueren, C., Belshaw, B.E. :
Canine Hypothyroidism - Etiology, Incidence, Symptoms, Diagnosis and Treatment Annales de Medecine Veterinaire 133:565-581, 1989.

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  • Created by Frank Nicholas on 06 Sep 2005