OMIA:000424-9685 : Goitre, familial in Felis catus (domestic cat)

In other species: chicken , dog , American black bear , pig , taurine cattle , goat , sheep , golden hamster , bongo , water buffalo

Categories: Endocrine / exocrine gland phene (incl mammary gland)

Links to possible relevant human trait(s) and/or gene(s) in OMIM: 274700 (trait) , 188450 (gene)

Links to relevant human diseases in MONDO:

Mendelian trait/disorder: unknown

Considered a defect: yes

Cross-species summary: Goitre is the enlargement of the thyroid gland, causing a swelling in the front of the neck. The condition can develop due to nutritional iodine deficiencies but familial forms of this disorder have been identified in several species. The molecular basis been determined for familial goitre in cattle and goats. Also spelt goiter.

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2005). OMIA:000424-9685: Online Mendelian Inheritance in Animals (OMIA) [dataset].


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2020 Iturriaga, M.P., Cocio, J.A., Barrs, V.R. :
Cluster of cases of congenital feline goitrous hypothyroidism in a single hospital. J Small Anim Pract 61:696-703, 2020. Pubmed reference: 32974927. DOI: 10.1111/jsap.13231.
1992 Jones, B.R., Gruffydd-Jones, T.J., Sparkes, A.H., Lucke, V.M. :
Preliminary Studies on Congenital Hypothyroidism in a Family of Abyssinian Cats Veterinary Record 131:145-148, 1992. Pubmed reference: 1329305.
1991 Sjollema, B.E., Denhartog, M.T., de Vijlder, J.J.M., Vandijk, J.E., Rijnberk, A. :
Congenital Hypothyroidism in Two Cats Due to Defective Organification - Data Suggesting Loosely Anchored Thyroperoxidase Acta Endocrinologica 125:435-440, 1991. Pubmed reference: 1659766.

Edit History

  • Created by Frank Nicholas on 06 Sep 2005