OMIA 000424-9685 : Goitre, familial in Felis catus

In other species: cattle , goat , dog , sheep , pig , chicken , bongo , water buffalo , golden hamster , American black bear

Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 274700 (trait) , 188450 (gene)

Mendelian trait/disorder: unknown

Considered a defect: yes

Cross-species summary: Enlargement of the thyroid gland, causing a swelling in the front of the neck. Familial forms of this disorder have been identified in several species. But only in cattle and goats has the molecular basis been determined. Also spelt goiter.


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
2020 Iturriaga, M.P., Cocio, J.A., Barrs, V.R. :
Cluster of cases of congenital feline goitrous hypothyroidism in a single hospital. J Small Anim Pract 61:696-703, 2020. Pubmed reference: 32974927. DOI: 10.1111/jsap.13231.
1992 Jones, B.R., Gruffydd-Jones, T.J., Sparkes, A.H., Lucke, V.M. :
Preliminary Studies on Congenital Hypothyroidism in a Family of Abyssinian Cats Veterinary Record 131:145-148, 1992. Pubmed reference: 1329305.
1991 Sjollema, B.E., Denhartog, M.T., de Vijlder, J.J.M., Vandijk, J.E., Rijnberk, A. :
Congenital Hypothyroidism in Two Cats Due to Defective Organification - Data Suggesting Loosely Anchored Thyroperoxidase Acta Endocrinologica 125:435-440, 1991. Pubmed reference: 1659766.

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  • Created by Frank Nicholas on 06 Sep 2005