OMIA 000595-9685 : Leukocyte adhesion deficiency, type I in Felis catus
|Symbol||Description||Species||Chr||Location||OMIA gene details page||Other Links|
|ITGB2||integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)||Felis catus||C2||NC_018731.3 (1762922..1788480)||ITGB2||Homologene, Ensembl, NCBI gene|
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WARNING! Inclusion of a variant in this table does not automatically mean that it should be used for DNA testing. Anyone contemplating the use of any of these variants for DNA testing should examine critically the relevant evidence (especially in breeds other than the breed in which the variant was first described). If it is decided to proceed, the location and orientation of the variant sequence should be checked very carefully.
|Breed(s)||Variant Phenotype||Gene||Allele||Type of Variant||Reference Sequence||Chr.||g. or m.||c. or n.||p.||Verbal Description||EVA ID||Year Published||PubMed ID(s)||Acknowledgements|
|Leukocyte adhesion deficiency, type I||ITGB2||ITGB-2 missing exon 2||deletion, gross (>20)||ICGSC Felis_catus_8.0||C2||g.1715627_1715650delGCCCTCTGGT||c.46_58Â +Â 11del||2017||28750142|
|2017||Bauer, T.R., Pratt, S.M., Palena, C.M., Raj, K., Giger, U., Bauer, T.R., Pratt, S.M., Palena, C.M., Raj, K., Giger, U. :|
|Feline leukocyte adhesion (CD18) deficiency caused by a deletion in the integrin β<sub>2</sub> (ITGB2) gene. Vet Clin Pathol 46:391-400, 2017. Pubmed reference: 28750142. DOI: 10.1111/vcp.12526.|
- Created by Frank Nicholas on 04 Aug 2017
- Changed by Frank Nicholas on 04 Aug 2017