OMIA 001041-9685 : Ventricular septal defect in Felis catus

In other species: cattle , chicken , dog , pig , sheep , horse , rabbit , alpaca

Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 614429 , 614431 , 614432

Mendelian trait/disorder: unknown

Considered a defect: yes

Cross-species summary: A congenital heart defect characterised by persistent patency (open-ness) of the ventricular septum, permitting flow of blood directly between ventricles, bypassing the pulmonary circulation and resulting in various degrees of cyanosis (blue discolouration of the skin) due to oxygen deficiency. Clinical signs include systolic murmur and a palpable thrill on both sides of the chest, dyspnoea and poor tolerance of exercise.

References


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
2015 Russell, D.S., Scansen, B.A., Himmel, L. :
Plexogenic pulmonary arteriopathy in a cat with non-restrictive ventricular septal defect and chronic pulmonary hypertension. J Small Anim Pract 56:524-9, 2015. Pubmed reference: 25728380. DOI: 10.1111/jsap.12341.
Tidholm, A., Ljungvall, I., Michal, J., Häggström, J., Höglund, K. :
Congenital heart defects in cats: A retrospective study of 162 cats (1996-2013). J Vet Cardiol 17 Suppl 1:S215-9, 2015. Pubmed reference: 26776580. DOI: 10.1016/j.jvc.2014.09.004.
2010 Dirven, M.J., Szatmári, V., Cornelissen, J.M., van den Ingh, T.S. :
[Case report: double-chambered right ventricle (DCRV), ventricular septal defect, and double caudal vena cava in a cat]. Tijdschr Diergeneeskd 135:180-8, 2010. Pubmed reference: 20334022.
2007 Riesen, S.C., Kovacevic, A., Lombard, C.W., Amberger, C. :
Prevalence of heart disease in symptomatic cats: an overview from 1998 to 2005. Schweiz Arch Tierheilkd 149:65-71, 2007. Pubmed reference: 17343132.
1983 Hawe, R.S. :
ECG of the month: ventricular septal defect in a cat. J Am Vet Med Assoc 182:364-5, 1983. Pubmed reference: 6833068.
1977 Eyster, G.E., Whipple, R.D., Anderson, L.K., Evans, A.T., O'Handley, P. :
Pulmonary artery banding for ventricular septal defect in dogs and cats. J Am Vet Med Assoc 170:434-8, 1977. Pubmed reference: 557030.
1973 van der Linde-Sipman, J.S., van der Ingh, T.S.G.A.M., Koeman, J.P. :
Congential heart abnormalities in the cat: a description of sixteen cases Zentralblatt fur Veterinarmedizin A 20:419-425, 1973.

Edit History


  • Created by Frank Nicholas on 06 Sep 2005
  • Changed by Frank Nicholas on 28 Nov 2011