OMIA:001041-30538 : Ventricular septal defect in Vicugna pacos
In other species: cattle , chicken , dog , pig , sheep , horse , domestic cat , rabbit , turkey , goat
Categories: Cardiovascular system phene
Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 614429 (trait) , 614431 (trait) , 614432 (trait)
Links to MONDO diseases: No links.
Mendelian trait/disorder: unknown
Considered a defect: yes
Cross-species summary: A congenital heart defect characterised by persistent patency (open-ness) of the ventricular septum, permitting flow of blood directly between ventricles, bypassing the pulmonary circulation and resulting in various degrees of cyanosis (blue discolouration of the skin) due to oxygen deficiency. Clinical signs include systolic murmur and a palpable thrill on both sides of the chest, dyspnoea and poor tolerance of exercise.
|2016||Stieger-Vanegas, S.M., Scollan, K.F., Meadows, L., Sisson, D., Schlipf, J., Riebold, T., Löhr, C.V. :|
|Cardiac-gated computed tomography angiography in three alpacas with complex congenital heart disease. J Vet Cardiol 18:88-98, 2016. Pubmed reference: 26803197 . DOI: 10.1016/j.jvc.2015.09.005.|
- Created by Frank Nicholas on 09 Nov 2016