OMIA:001041-30538 : Ventricular septal defect in Vicugna pacos

In other species: cattle , chicken , dog , pig , sheep , horse , domestic cat , rabbit , turkey , goat

Categories: Cardiovascular system phene

Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 614429 (trait) , 614431 (trait) , 614432 (trait)

Links to MONDO diseases: No links.

Mendelian trait/disorder: unknown

Considered a defect: yes

Cross-species summary: A congenital heart defect characterised by persistent patency (open-ness) of the ventricular septum, permitting flow of blood directly between ventricles, bypassing the pulmonary circulation and resulting in various degrees of cyanosis (blue discolouration of the skin) due to oxygen deficiency. Clinical signs include systolic murmur and a palpable thrill on both sides of the chest, dyspnoea and poor tolerance of exercise.


2016 Stieger-Vanegas, S.M., Scollan, K.F., Meadows, L., Sisson, D., Schlipf, J., Riebold, T., Löhr, C.V. :
Cardiac-gated computed tomography angiography in three alpacas with complex congenital heart disease. J Vet Cardiol 18:88-98, 2016. Pubmed reference: 26803197 . DOI: 10.1016/j.jvc.2015.09.005.

Edit History

  • Created by Frank Nicholas on 09 Nov 2016