OMIA:001041-9913 : Ventricular septal defect in Bos taurus (taurine cattle)
Categories: Cardiovascular system phene
Links to MONDO diseases: No links.
Mendelian trait/disorder: unknown
Considered a defect: yes
Cross-species summary: A congenital heart defect characterised by persistent patency (open-ness) of the ventricular septum, permitting flow of blood directly between ventricles, bypassing the pulmonary circulation and resulting in various degrees of cyanosis (blue discolouration of the skin) due to oxygen deficiency. Clinical signs include systolic murmur and a palpable thrill on both sides of the chest, dyspnoea and poor tolerance of exercise.
Have human generated variants been created, e.g. through genetic engineering and gene editing
Cite this entry
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
|2023||Mee, J.F., Murphy, D., Curran, M. :|
|Bovine congenital defects recorded by veterinary practitioners. Reprod Domest Anim , 2023. Pubmed reference: 37975255. DOI: 10.1111/rda.14501.|
|2015||Depenbrock, S.M., Visser, L.C., Kohnken, R.A., Russell, D.S., Simpson, K.M., Bonagura, J.D. :|
|Congenital isolated cleft mitral valve leaflet and apical muscular ventricular septal defect in a Holstein calf. J Vet Cardiol 17:237-42, 2015. Pubmed reference: 26263841. DOI: 10.1016/j.jvc.2015.03.003.|
|1994||Penrith, M.L., Bastianello, S.S., Petzer, I.M. :|
|Congenital Cardiac Defects in Two Closely Related Jersey Calves Journal of the South African Veterinary Association - Tydskrif Van Die Suid - Afrikaanse Veterinere Vereniging 65:31-35, 1994.|
- Created by Frank Nicholas on 06 Sep 2005