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OMIA:001041-9913 : Ventricular septal defect in Bos taurus (taurine cattle)

In other species: chicken , turkey , dog , domestic cat , horse , pig , goat , sheep , rabbit , alpaca

Categories: Cardiovascular system phene

Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 614429 (trait) , 614431 (trait) , 614432 (trait)

Links to MONDO diseases: No links.

Mendelian trait/disorder: unknown

Considered a defect: yes

Cross-species summary: A congenital heart defect characterised by persistent patency (open-ness) of the ventricular septum, permitting flow of blood directly between ventricles, bypassing the pulmonary circulation and resulting in various degrees of cyanosis (blue discolouration of the skin) due to oxygen deficiency. Clinical signs include systolic murmur and a palpable thrill on both sides of the chest, dyspnoea and poor tolerance of exercise.

Genetic engineering: Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2005). OMIA:001041-9913: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70

References

Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2023 Mee, J.F., Murphy, D., Curran, M. :
Bovine congenital defects recorded by veterinary practitioners. Reprod Domest Anim , 2023. Pubmed reference: 37975255. DOI: 10.1111/rda.14501.
2015 Depenbrock, S.M., Visser, L.C., Kohnken, R.A., Russell, D.S., Simpson, K.M., Bonagura, J.D. :
Congenital isolated cleft mitral valve leaflet and apical muscular ventricular septal defect in a Holstein calf. J Vet Cardiol 17:237-42, 2015. Pubmed reference: 26263841. DOI: 10.1016/j.jvc.2015.03.003.
1994 Penrith, M.L., Bastianello, S.S., Petzer, I.M. :
Congenital Cardiac Defects in Two Closely Related Jersey Calves Journal of the South African Veterinary Association - Tydskrif Van Die Suid - Afrikaanse Veterinere Vereniging 65:31-35, 1994.

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  • Created by Frank Nicholas on 06 Sep 2005