OMIA:001607-158456 : Skin colour in Betta splendens (Siamese fighting fish)

In other species: goldfish , rainbow trout , guppy , Nile tilapia , gilthead seabream , common lizard , Mallard , Garter snake , Guadeloupean anole , sailfin molly , ball python , Midas cichlid , blacktip shark , common wall lizard , Italian wall lizard , Sand lizard , common chameleon , flapneck chameleon , mimic poison frog , Asian bonytongue , leopard coralgrouper , White's rock-skink , , starry flounder , delicate skink , red-top cobalt mbuna , Sagus Kul lizard , toad-headed agama , Oujiang color common carp , poison dart frogs , Blue Regal "Mbenji" Peacock

Categories: Pigmentation phene

Links to MONDO diseases: No links.

Mendelian trait/disorder: unknown

Considered a defect: no

Species-specific description: Palmiotti et al. (2023) "knocked out three genes: alkal2l, bco1l, and mitfa, and analyzed their effects on viability and pigmentation. ... [The authors concluded that their] method for obtaining CRISPR/Cas9 knockouts in betta is efficient and effective, that a homozygous knockout of bco1l is lethal, and that alkal2l is critical for blue coloration." This study involves genetically modified organisms (GMO).

Genetic engineering: Yes - in addition to the occurrence of natural variants, variants have been created artificially, e.g. by genetic engineering or gene editing
Have human generated variants been created, e.g. through genetic engineering and gene editing

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2023). OMIA:001607-158456: Online Mendelian Inheritance in Animals (OMIA) [dataset].


2023 Palmiotti, A., Lichak, M.R., Shih, P.Y., Kwon, Y.M., Bendesky, A. :
Genetic manipulation of betta fish. Front Genome Ed 5:1167093, 2023. Pubmed reference: 37545763. DOI: 10.3389/fgeed.2023.1167093.

Edit History

  • Created by Imke Tammen2 on 10 Aug 2023
  • Changed by Imke Tammen2 on 18 Dec 2023