OMIA:001607-158456 : Skin colour in Betta splendens (Siamese fighting fish)
In other species: goldfish , rainbow trout , guppy , Nile tilapia , gilthead seabream , Mallard , Garter snake , Guadeloupean anole , ball python , Midas cichlid , blacktip shark , common wall lizard , Sand lizard , mimic poison frog , Asian bonytongue , leopard coralgrouper , White's rock-skink , starry flounder , delicate skink , red-top cobalt mbuna , Sagus Kul lizard , Oujiang color common carp , poison dart frogs , Blue Regal "Mbenji" Peacock
Categories: Pigmentation phene
Links to MONDO diseases: No links.
Mendelian trait/disorder: unknown
Considered a defect: no
Species-specific description: Palmiotti et al. (2023) "knocked out three genes: alkal2l, bco1l, and mitfa, and analyzed their effects on viability and pigmentation. ... [The authors concluded that their] method for obtaining CRISPR/Cas9 knockouts in betta is efficient and effective, that a homozygous knockout of bco1l is lethal, and that alkal2l is critical for blue coloration." This study involves genetically modified organisms (GMO).
Have human generated variants been created, e.g. through genetic engineering and gene editing
Cite this entry
|2023||Palmiotti, A., Lichak, M.R., Shih, P.Y., Kwon, Y.M., Bendesky, A. :|
|Genetic manipulation of betta fish. Front Genome Ed 5:1167093, 2023. Pubmed reference: 37545763. DOI: 10.3389/fgeed.2023.1167093.|
- Created by Imke Tammen2 on 10 Aug 2023