OMIA:001607-158456 : Skin colour in Betta splendens (Siamese fighting fish)

In other species: goldfish , rainbow trout , guppy , Nile tilapia , gilthead seabream , Mallard , Garter snake , Guadeloupean anole , ball python , Midas cichlid , blacktip shark , common wall lizard , Sand lizard , mimic poison frog , Asian bonytongue , leopard coralgrouper , White's rock-skink , starry flounder , delicate skink , red-top cobalt mbuna , Sagus Kul lizard , Oujiang color common carp , poison dart frogs , Blue Regal "Mbenji" Peacock

Categories: Pigmentation phene

Links to MONDO diseases: No links.

Mendelian trait/disorder: unknown

Considered a defect: no

Species-specific description: Palmiotti et al. (2023) "knocked out three genes: alkal2l, bco1l, and mitfa, and analyzed their effects on viability and pigmentation. ... [The authors concluded that their] method for obtaining CRISPR/Cas9 knockouts in betta is efficient and effective, that a homozygous knockout of bco1l is lethal, and that alkal2l is critical for blue coloration." This study involves genetically modified organisms (GMO).

Genetic engineering: Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2023). OMIA:001607-158456: Online Mendelian Inheritance in Animals (OMIA) [dataset].


2023 Palmiotti, A., Lichak, M.R., Shih, P.Y., Kwon, Y.M., Bendesky, A. :
Genetic manipulation of betta fish. Front Genome Ed 5:1167093, 2023. Pubmed reference: 37545763. DOI: 10.3389/fgeed.2023.1167093.

Edit History

  • Created by Imke Tammen2 on 10 Aug 2023