OMIA:002229-34892 : Hypotrichosis, HR-related in Neophocaena phocaenoides

In other species: domestic cat , sheep , bottlenosed dolphin , long-beaked common dolphin , beluga whale , Yangtze River dolphin , minke whale , Omura's baleen whale , pig

Categories: Integument (skin) phene

Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 203655 (trait) , 602302 (gene)

Links to MONDO diseases: No links.

Mendelian trait/disorder: yes

Considered a defect: no

Key variant known: yes

Year key variant first reported: 2013

Cross-species summary: Also known as Hairless

Molecular basis: Chen et al. (2013) reported evidence that the HR gene in cetaceans, including Neophocaena phocaenoides, has degenerated into a non-functional pseudogene, which is consistent with the hairlessness of this species.

Associated gene:

Symbol Description Species Chr Location OMIA gene details page Other Links
HR Neophocaena phocaenoides - no genomic information (-..-) HR Ensembl

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2020). OMIA:002229-34892: Online Mendelian Inheritance in Animals (OMIA) [dataset].


2013 Chen, Z., Wang, Z., Xu, S., Zhou, K., Yang, G. :
Characterization of hairless (Hr) and FGF5 genes provides insights into the molecular basis of hair loss in cetaceans. BMC Evol Biol 13:34, 2013. Pubmed reference: 23394579 . DOI: 10.1186/1471-2148-13-34.

Edit History

  • Created by Frank Nicholas on 27 Jan 2020