OMIA:003066-10036 : Genetically engineered gene knockout or knockin, generic in Mesocricetus auratus (golden hamster) |
In other species: grass carp , Japanese medaka , Nile tilapia , pig , turquoise killifish
Categories: Cellular phene
Single-gene trait/disorder: unknown
Disease-related: unknown
Cross-species summary: Gene knockout and knockin models comprise genetically engineered animals in which specific genes have been inactivated or deleted or added. These models provide a valuable tool for investigating gene function, disease mechanisms, and biological processes. See also gene specific entries (by doing an exhaustive search for GMO) and/or entires for OMIA:002665 Genetically engineered humanised animal.
Genetic engineering:
Yes - variants have been created artificially, e.g. by genetic engineering or gene editing
Have human generated variants been created, e.g. through genetic engineering and gene editing
Associated genes:
| Symbol | Description | Species | Chr | Location | OMIA gene details page | Other Links |
|---|---|---|---|---|---|---|
| Tdrd15 | tudor domain containing 15 | Mesocricetus auratus | NW_024429205.1 (15412380..15428492) | Tdrd15 | Ensembl, NCBI gene | |
| Apoa5 | apolipoprotein A5 | Mesocricetus auratus | NW_024429203.1 (24944502..24947612) | Apoa5 | Ensembl, NCBI gene | |
| Avpr1a | arginine vasopressin receptor 1A | Mesocricetus auratus | NW_024429195.1 (48918690..48914423) | Avpr1a | Ensembl, NCBI gene | |
| Lepr | leptin receptor | Mesocricetus auratus | NW_024429197.1 (38204791..38122591) | Lepr | Ensembl, NCBI gene | |
| Apof | apolipoprotein F | Mesocricetus auratus | NW_024429195.1 (43892863..43891495) | Apof | Ensembl, NCBI gene |
Contact us
If you notice anything missing or in need of change, please contact us at: [email protected].
Cite this entry
Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2026). OMIA:003066-10036: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70
References
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
| 2026 | Aspesi, D., Vu, H., Rivers, I., Stoehr, M.C., Huhman, K.L., Albers, H.E. : |
| Nonlinear and sex-specific effects of V1aR deletion on juvenile social behavior. Front Endocrinol (Lausanne) 17:1901426, 2026. Pubmed reference: 42774051. DOI: 10.3389/fendo.2026.1901426. | |
| Chen, W., Zhang, X., Fan, R., Li, X., Guan, F., Wan, G., Kong, W., Qi, X., Pan, S., Shi, S., Su, Y., Gao, S., Huang, W., Xian, X., Liu, J., Wang, Y., Ma, Y. : | |
| Generating golden Syrian hamsters with conditional alleles via zygote microinjection of CRISPR/Cas9. Animal Model Exp Med 9:308-318, 2026. Pubmed reference: 41235827. DOI: 10.1002/ame2.70107. | |
| Liu, Y., Roszkowski, E., Li, R., Sisson, C., Landman, E., Weaver, D.R., Wang, Z., Evans, J.A., Bittman, E.L. : | |
| Circadian behavioral and bioluminescence rhythms in the Per2 LUC Syrian Hamster. J Biol Rhythms :7487304261459487, 2026. Pubmed reference: 42415525. DOI: 10.1177/07487304261459487. | |
| Tang, X., Lu, J., Long, L., Huang, M., Zeng, W., Zhang, A., Chen, Q., Shi, A., Li, J., Gao, Y. : | |
| A novel LepR knockout hamster model for type 2 diabetes and its complications: a complementary platform to conventional rodent models. Front Endocrinol (Lausanne) 17:1866850, 2026. Pubmed reference: 42666243. DOI: 10.3389/fendo.2026.1866850. | |
| 2025 | Zhu, M., Xiang, Y., Wang, H., Zhao, S., Zeng, W., Li, J., Yao, B. : |
| Tdrd15 is dispensable for male fertility and spermatogenesis in the golden hamster. Eur J Med Res 30:1013, 2025. Pubmed reference: 41126281. DOI: 10.1186/s40001-025-03285-w. | |
| 2024 | Guo, J., Miao, G., Zhang, W., Shi, H., Lai, P., Xu, Y., Zhang, L., Chen, G., Han, Y., Zhao, Y., Liu, G., Zhang, L., Wang, Y., Huang, W., Xian, X. : |
| Depletion of ApoA5 aggravates spontaneous and diet-induced nonalcoholic fatty liver disease by reducing hepatic NR1D1 in hamsters. Theranostics 14:2036-2057, 2024. Pubmed reference: 38505614. DOI: 10.7150/thno.91084. |
Edit History
- Created by Imke Tammen on 25 Jul 2026
- Changed by Imke Tammen on 25 Jul 2026
- Changed by Imke Tammen on 05 Oct 2026