OMIA:003066-10036 : Genetically engineered gene knockout or knockin, generic in Mesocricetus auratus (golden hamster)

In other species: grass carp , Japanese medaka , Nile tilapia , pig , turquoise killifish

Categories: Cellular phene

Single-gene trait/disorder: unknown

Disease-related: unknown

Cross-species summary: Gene knockout and knockin models comprise genetically engineered animals in which specific genes have been inactivated or deleted or added. These models provide a valuable tool for investigating gene function, disease mechanisms, and biological processes. See also gene specific entries (by doing an exhaustive search for GMO) and/or entires for OMIA:002665  Genetically engineered humanised animal.

Genetic engineering: Yes - variants have been created artificially, e.g. by genetic engineering or gene editing
Have human generated variants been created, e.g. through genetic engineering and gene editing

Associated genes:

Symbol Description Species Chr Location OMIA gene details page Other Links
Tdrd15 tudor domain containing 15 Mesocricetus auratus NW_024429205.1 (15412380..15428492) Tdrd15 Ensembl, NCBI gene
Apoa5 apolipoprotein A5 Mesocricetus auratus NW_024429203.1 (24944502..24947612) Apoa5 Ensembl, NCBI gene

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Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2026). OMIA:003066-10036: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70

References

Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2026 Liu, Y., Roszkowski, E., Li, R., Sisson, C., Landman, E., Weaver, D.R., Wang, Z., Evans, J.A., Bittman, E.L. :
Circadian behavioral and bioluminescence rhythms in the Per2 LUC Syrian Hamster. J Biol Rhythms :7487304261459487, 2026. Pubmed reference: 42415525. DOI: 10.1177/07487304261459487.
2025 Zhu, M., Xiang, Y., Wang, H., Zhao, S., Zeng, W., Li, J., Yao, B. :
Tdrd15 is dispensable for male fertility and spermatogenesis in the golden hamster. Eur J Med Res 30:1013, 2025. Pubmed reference: 41126281. DOI: 10.1186/s40001-025-03285-w.
2024 Guo, J., Miao, G., Zhang, W., Shi, H., Lai, P., Xu, Y., Zhang, L., Chen, G., Han, Y., Zhao, Y., Liu, G., Zhang, L., Wang, Y., Huang, W., Xian, X. :
Depletion of ApoA5 aggravates spontaneous and diet-induced nonalcoholic fatty liver disease by reducing hepatic NR1D1 in hamsters. Theranostics 14:2036-2057, 2024. Pubmed reference: 38505614. DOI: 10.7150/thno.91084.

Edit History


  • Created by Imke Tammen on 25 Jul 2026
  • Changed by Imke Tammen on 25 Jul 2026