OMIA:003066-9823 : Genetically engineered gene knockout or knockin, generic in Sus scrofa (pig) |
In other species: grass carp , Japanese medaka , Nile tilapia , golden hamster , turquoise killifish
Categories: Cellular phene
Single-gene trait/disorder: unknown
Disease-related: unknown
Cross-species summary: Gene knockout and knockin models comprise genetically engineered animals in which specific genes have been inactivated or deleted or added. These models provide a valuable tool for investigating gene function, disease mechanisms, and biological processes. See also gene specific entries (by doing an exhaustive search for GMO) and/or entires for OMIA:002665 Genetically engineered humanised animal.
Genetic engineering:
Yes - variants have been created artificially, e.g. by genetic engineering or gene editing
Have human generated variants been created, e.g. through genetic engineering and gene editing
Associated genes:
| Symbol | Description | Species | Chr | Location | OMIA gene details page | Other Links |
|---|---|---|---|---|---|---|
| WNT2 | Wnt family member 2 | Sus scrofa | 18 | NC_139400.1 (37841599..37888990) | WNT2 | Ensembl, NCBI gene |
| WNT2B | Wnt family member 2B | Sus scrofa | 4 | NC_139386.1 (113103760..113090357) | WNT2B | Ensembl, NCBI gene |
Contact us
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Cite this entry
Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2026). OMIA:003066-9823: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70
Reference
| 2025 | Tian, S., Zong, R., Zhang, Y., Liu, Q., Wang, L., Wang, Y., Zhao, J. : |
| WNT2/2B double homologous knockout blocks lung development and formation in pigs. Sci China Life Sci 68:3410-3412, 2025. Pubmed reference: 40614013. DOI: 10.1007/s11427-024-2936-y. |
Edit History
- Created by Imke Tammen on 25 Jul 2026