OMIA:003066-105023 : Genetically engineered gene knockout or knockin, generic in Nothobranchius furzeri (turquoise killifish) |
In other species: grass carp , Japanese medaka , Nile tilapia , pig , golden hamster
Categories: Cellular phene
Single-gene trait/disorder: unknown
Disease-related: unknown
Cross-species summary: Gene knockout and knockin models comprise genetically engineered animals in which specific genes have been inactivated or deleted or added. These models provide a valuable tool for investigating gene function, disease mechanisms, and biological processes. See also gene specific entries (by doing an exhaustive search for GMO) and/or entires for OMIA:002665 Genetically engineered humanised animal.
Genetic engineering:
Yes - variants have been created artificially, e.g. by genetic engineering or gene editing
Have human generated variants been created, e.g. through genetic engineering and gene editing
Associated genes:
| Symbol | Description | Species | Chr | Location | OMIA gene details page | Other Links |
|---|---|---|---|---|---|---|
| mitfa | melanocyte inducing transcription factor a | Nothobranchius furzeri | 3 | NC_091743.1 (44701408..44660729) | mitfa | Ensembl, NCBI gene |
| ltk | leukocyte receptor tyrosine kinase | Nothobranchius furzeri | 18 | NC_091758.1 (30745782..30679407) | ltk | Ensembl, NCBI gene |
| csf1ra | colony stimulating factor 1 receptor, a | Nothobranchius furzeri | 1 | NC_091741.1 (96079400..96067313) | csf1ra | Ensembl, NCBI gene |
Contact us
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Cite this entry
Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2026). OMIA:003066-105023: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70
References
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
| 2026 | Krug, J., Perner, B., Albertz, C., Mörl, H., Hopfenmüller, V.L., Englert, C. : |
| Correction: Generation of a transparent killifish line through multiplex CRISPR/Cas9mediated gene inactivation. Elife 15:e112412, 2026. Pubmed reference: 42360161. DOI: 10.7554/eLife.112412. | |
| 2023 | Krug, J., Perner, B., Albertz, C., Mörl, H., Hopfenmüller, V.L., Englert, C. : |
| Generation of a transparent killifish line through multiplex CRISPR/Cas9mediated gene inactivation. Elife 12:e81549, 2023. Pubmed reference: 36820520. DOI: 10.7554/eLife.81549. |
Edit History
- Created by Imke Tammen on 25 Jul 2026
- Changed by Imke Tammen on 25 Jul 2026