OMIA:003066-7959 : Genetically engineered gene knockout or knockin, generic in Ctenopharyngodon idella (grass carp) |
In other species: Japanese medaka , Nile tilapia , pig , golden hamster , turquoise killifish
Categories: Cellular phene
Single-gene trait/disorder: unknown
Disease-related: unknown
Cross-species summary: Gene knockout and knockin models comprise genetically engineered animals in which specific genes have been inactivated or deleted or added. These models provide a valuable tool for investigating gene function, disease mechanisms, and biological processes. See also gene specific entries (by doing an exhaustive search for GMO) and/or entires for OMIA:002665 Genetically engineered humanised animal.
Genetic engineering:
Yes - variants have been created artificially, e.g. by genetic engineering or gene editing
Have human generated variants been created, e.g. through genetic engineering and gene editing
Associated gene:
| Symbol | Description | Species | Chr | Location | OMIA gene details page | Other Links |
|---|---|---|---|---|---|---|
| pik3r1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | Ctenopharyngodon idella | 5 | NC_067224.1 (10058454..10090886) | pik3r1 | Ensembl, NCBI gene |
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Cite this entry
Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2026). OMIA:003066-7959: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70
Reference
| 2026 | Lv, W., Meng, X., Sun, T., Chen, Y., Li, W., Sheng, T., Cong, Q., Yu, Q., He, R., He, R., Shen, Y., Ren, J., Qiu, J., Gui, L., Li, J., Xu, X. : |
| Disruption of Pik3r1 promotes muscle hyperplasia and lipolysis in grass carp (Ctenopharyngodon idella). Comp Biochem Physiol A Mol Integr Physiol 319:S1095-6433(26)00080-2:112044, 2026. Pubmed reference: 42379511. DOI: 10.1016/j.cbpa.2026.112044. |
Edit History
- Created by Imke Tammen on 25 Jul 2026
- Changed by Imke Tammen on 25 Jul 2026