OMIA:000033-10141 : Alzheimer-like disease, generic in Cavia porcellus (domestic guinea pig)

In other species: white-tufted-ear marmoset , crab-eating macaque , Rhesus monkey , hamadryas baboon , dog , domestic cat , saddleback dolphin , long-finned pilot whale , striped dolphin , bottlenosed dolphin , Cuvier's beaked whale , pig , sheep , degu , white-beaked dolphin , northern tree shrew , short-finned pilot whale , Blainville's beaked whale , green monkey , Indo-pacific bottlenose dolphin , Atlantic spotted dolphin , Chinese tree shrew , black-striped capuchin

Categories: Nervous system phene

Links to possible relevant human trait(s) and/or gene(s) in OMIM: 104300 (trait) , 104310 (trait) , 502500 (trait) , 607822 (trait) , 606889 (trait)

Single-gene trait/disorder: unknown

Disease-related: yes

Cross-species summary: renamed from Alzheimer disease, generic to Alzheimer-like disease, generic [20/07/2023].

Contact us

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Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2025). OMIA:000033-10141: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70

References

Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2025 Kayano, M. :
Exploring efficient and effective mammalian models for Alzheimer's disease. Front Aging Neurosci 17:1652754, 2025. Pubmed reference: 40893124. DOI: 10.3389/fnagi.2025.1652754.
2022 Wahl, D., Moreno, J.A., Santangelo, K.S., Zhang, Q., Afzali, M.F., Walsh, M.A., Musci, R.V., Cavalier, A.N., Hamilton, K.L., LaRocca, T.J. :
Nontransgenic guinea pig strains exhibit hallmarks of human brain aging and Alzheimer's disease. J Gerontol A Biol Sci Med Sci 77:1766-1774, 2022. Pubmed reference: 35323931. DOI: 10.1093/gerona/glac073.
2014 Bates, K., Vink, R., Martins, R., Harvey, A. :
Aging, cortical injury and Alzheimer's disease-like pathology in the guinea pig brain. Neurobiol Aging 35:S0197-4580(13)00588-5:1345-51, 2014. Pubmed reference: 24360504. DOI: 10.1016/j.neurobiolaging.2013.11.020.
2013 Sharman, M.J., Moussavi Nik, S.H., Chen, M.M., Ong, D., Wijaya, L., Laws, S.M., Taddei, K., Newman, M., Lardelli, M., Martins, R.N., Verdile, G. :
The guinea pig as a model for sporadic Alzheimer's disease (AD): The impact of cholesterol intake on expression of AD-related genes. PLoS One 8:e66235, 2013. Pubmed reference: 23805206. DOI: 10.1371/journal.pone.0066235.

Edit History


  • Created by Imke Tammen2 on 09 Sep 2025
  • Changed by Imke Tammen2 on 09 Sep 2025