OMIA:000033-10160 : Alzheimer-like disease, generic in Octodon degus (degu)
In other species: crab-eating macaque , Rhesus monkey , dog , domestic cat , saddleback dolphin , long-finned pilot whale , striped dolphin , Cuvier's beaked whale , pig , sheep , white-beaked dolphin , Blainville's beaked whale , green monkey , Indo-pacific bottlenose dolphin , Atlantic spotted dolphin , Chinese tree shrew
Categories: Nervous system phene
Links to MONDO diseases: No links.
Mendelian trait/disorder: unknown
Considered a defect: yes
Cross-species summary: renamed from Alzheimer disease, generic to Alzheimer-like disease, generic [20/07/2023].
Have human generated variants been created, e.g. through genetic engineering and gene editing
Cite this entry
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
|2012||Ardiles, A.O., Tapia-Rojas, C.C., Mandal, M., Alexandre, F., Kirkwood, A., Inestrosa, N.C., Palacios, A.G. :|
|Postsynaptic dysfunction is associated with spatial and object recognition memory loss in a natural model of Alzheimer's disease. Proc Natl Acad Sci U S A 109:13835-40, 2012. Pubmed reference: 22869717. DOI: 10.1073/pnas.1201209109.|
|2011||van Groen, T., Kadish, I., Popović, N., Popović, M., Caballero-Bleda, M., Baño-Otálora, B., Vivanco, P., Rol, M.Á., Madrid, J.A. :|
|Age-related brain pathology in Octodon degu: blood vessel, white matter and Alzheimer-like pathology. Neurobiol Aging 32:1651-61, 2011. Pubmed reference: 19910078. DOI: 10.1016/j.neurobiolaging.2009.10.008.|
- Created by Frank Nicholas on 01 Aug 2013