OMIA:000033-10160 : Alzheimer-like disease, generic in Octodon degus (degu)

In other species: crab-eating macaque , Rhesus monkey , dog , domestic cat , saddleback dolphin , long-finned pilot whale , striped dolphin , Cuvier's beaked whale , pig , sheep , white-beaked dolphin , Blainville's beaked whale , green monkey , Indo-pacific bottlenose dolphin , Atlantic spotted dolphin , Chinese tree shrew

Categories: Nervous system phene

Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 104300 (trait) , 104310 (trait) , 502500 (trait) , 607822 (trait) , 606889 (trait)

Links to MONDO diseases: No links.

Mendelian trait/disorder: unknown

Considered a defect: yes

Cross-species summary: renamed from Alzheimer disease, generic to Alzheimer-like disease, generic [20/07/2023].

Genetic engineering: Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2013). OMIA:000033-10160: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70

References

Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2012 Ardiles, A.O., Tapia-Rojas, C.C., Mandal, M., Alexandre, F., Kirkwood, A., Inestrosa, N.C., Palacios, A.G. :
Postsynaptic dysfunction is associated with spatial and object recognition memory loss in a natural model of Alzheimer's disease. Proc Natl Acad Sci U S A 109:13835-40, 2012. Pubmed reference: 22869717. DOI: 10.1073/pnas.1201209109.
2011 van Groen, T., Kadish, I., Popović, N., Popović, M., Caballero-Bleda, M., Baño-Otálora, B., Vivanco, P., Rol, M.Á., Madrid, J.A. :
Age-related brain pathology in Octodon degu: blood vessel, white matter and Alzheimer-like pathology. Neurobiol Aging 32:1651-61, 2011. Pubmed reference: 19910078. DOI: 10.1016/j.neurobiolaging.2009.10.008.

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  • Created by Frank Nicholas on 01 Aug 2013