OMIA:000033-9544 : Alzheimer-like disease, generic in Macaca mulatta (Rhesus monkey)

In other species: crab-eating macaque , dog , domestic cat , saddleback dolphin , long-finned pilot whale , striped dolphin , Cuvier's beaked whale , pig , sheep , degu , white-beaked dolphin , Blainville's beaked whale , green monkey , Indo-pacific bottlenose dolphin , Atlantic spotted dolphin , Chinese tree shrew , black-striped capuchin

Categories: Nervous system phene

Links to possible relevant human trait(s) and/or gene(s) in OMIM: 104300 (trait) , 104310 (trait) , 502500 (trait) , 607822 (trait) , 606889 (trait)

Mendelian trait/disorder: unknown

Considered a defect: yes

Cross-species summary: renamed from Alzheimer disease, generic to Alzheimer-like disease, generic [20/07/2023].

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2023). OMIA:000033-9544: Online Mendelian Inheritance in Animals (OMIA) [dataset].


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2024 Jiang, Z., Wang, J., Qin, Y., Liu, S., Luo, B., Bai, F., Wei, H., Zhang, S., Wei, J., Ding, G., Ma, L., He, S., Chen, R., Sun, Y., Chen, Y., Wang, L., Xu, H., Wang, X., Chen, G., Lei, W. :
A nonhuman primate model with Alzheimer's disease-like pathology induced by hippocampal overexpression of human tau. Alzheimers Res Ther 16:22, 2024. Pubmed reference: 38281031. DOI: 10.1186/s13195-024-01392-0.
Pan, M.T., Zhang, H., Li, X.J., Guo, X.Y. :
Genetically modified non-human primate models for research on neurodegenerative diseases. Zool Res 45:2095-8137(2024)02-0263-12:263-274, 2024. Pubmed reference: 38287907. DOI: 10.24272/j.issn.2095-8137.2023.197.
Thomas, J.L., Nilaver, B.I., Lomniczi, A., Brown, D.I., Appleman, M.L., Kohama, S.G., Urbanski, H.F. :
Pathological markers of Alzheimer's disease and related dementia in the rhesus macaque amygdala. J Alzheimers Dis Rep 8:25-32, 2024. Pubmed reference: 38229831. DOI: 10.3233/ADR-230184.
2023 Datta, D. :
Interrogating the etiology of sporadic Alzheimer's disease using aging Rhesus macaques: Cellular, molecular and cortical circuitry perspectives. J Gerontol A Biol Sci Med Sci , 2023. Pubmed reference: 37279946. DOI: 10.1093/gerona/glad134.
Iwaide, S., Nakayama, Y., Chambers, J.K., Uchida, K., Nakagawa, D., Yamanashi, Y., Bando, H., Murakami, T. :
Senile plaques and phosphorylated tau deposition in a super-aged rhesus monkey (Macaca mulatta). J Vet Med Sci , 2023. Pubmed reference: 37821381. DOI: 10.1292/jvms.23-0313.
2021 Beckman, D., Chakrabarty, P., Ott, S., Dao, A., Zhou, E., Janssen, W.G., Donis-Cox, K., Muller, S., Kordower, J.H., Morrison, J.H. :
A novel tau-based rhesus monkey model of Alzheimer's pathogenesis. Alzheimers Dement 17:933-945, 2021. Pubmed reference: 33734581. DOI: 10.1002/alz.12318.

Edit History

  • Created by Imke Tammen2 on 08 Jun 2023