OMIA:000202-143630 : Coat colour, oculocutaneous albinism type I (OCA1), TYR-related in Paroedura picta (ocelot gecko)

In other species: Japanese medaka , dark-spotted frog , Japanese wrinkled frog , Tufted capuchin , Rhesus monkey , hamadryas baboon , dog , red fox , domestic ferret , domestic cat , lion , humpback whale , ass (donkey) , pig , red deer , American bison , taurine cattle , rabbit , golden hamster , Mongolian gerbil , domestic guinea pig , Japanese ratsnake , water buffalo , four-striped grass mouse , American mink , Japanese raccoon dog , Rice frog

Categories: Pigmentation phene

Links to possible relevant human trait(s) and/or gene(s) in OMIM: 203100 (trait) , 606952 (trait) , 606933 (gene)

Mendelian trait/disorder: unknown

Considered a defect: unknown

Cross-species summary: Congenital lack of pigment in most parts of the body. Due to a non-functional form of the enzyme tyrosinase. Also known as Oculocutaneous albinism (OCA), Acromelanism and as the Himalayan coat-colour pattern

Species-specific description: This phene includes references to studies involving gene edited or genetically modified organisms (GMO).

Genetic engineering: Yes - variants have been created artificially, e.g. by genetic engineering or gene editing
Have human generated variants been created, e.g. through genetic engineering and gene editing

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2023). OMIA:000202-143630: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70

Reference

2023 Abe, T., Kaneko, M., Kiyonari, H. :
A reverse genetic approach in geckos with the CRISPR/Cas9 system by oocyte microinjection. Dev Biol 497:S0012-1606(23)00032-5:26-32, 2023. Pubmed reference: 36868446. DOI: 10.1016/j.ydbio.2023.02.005.

Edit History


  • Created by Imke Tammen2 on 09 Mar 2023
  • Changed by Imke Tammen2 on 20 Sep 2023
  • Changed by Imke Tammen2 on 10 Dec 2023