OMIA 000202-9773 : Coat colour, albinism in Megaptera novaeangliae

In other species: domestic cat , cattle , dog , rabbit , sheep , Sumatran tiger , western chorus frog , grass carp , golden hamster , gray short-tailed opossum , raccoon , meadow voles , water buffalo , Arizona pocket mouse , nutria , eastern chipmunk , rufous rat-kangaroo , hippopotamus , hares , northern pocket gopher , North American deer mouse , ass , Japanese medaka , rainbow trout , brown bear , American mink , grivet , goldfish , Campbell's desert hamster , axolotl , African clawed frog , turkey vulture , American black bear , domestic ferret , pig , domestic guinea pig , Tufted capuchin , dark-spotted frog , Japanese wrinkled frog , Rice frog , Bornean orangutan , lion

Possibly relevant human trait(s) and/or gene(s) (MIM number): 203100

Mendelian trait/disorder: yes

Mode of inheritance: Autosomal Recessive

Considered a defect: yes

Key variant known: yes

Year key variant first reported: 2011

Cross-species summary: Congenital lack of pigment in all parts of the body. Due to a non-functional form of the enzyme tyrosinase. Also known as Oculocutaneous albinism (OCA)

Associated gene:

Symbol Description Species Chr Location OMIA gene details page Other Links
TYR Megaptera novaeangliae - no genomic information (-..-) TYR Ensembl

Reference


2011 Polanowski, A.M., Robinson-Laverick, S.M., Paton, D., Jarman, S.N. :
Variation in the tyrosinase gene associated with a white humpback whale (Megaptera novaeangliae). J Hered 103:130-3, 2011. Pubmed reference: 22140253. DOI: 10.1093/jhered/esr108.

Edit History


  • Created by Frank Nicholas on 07 Dec 2011
  • Changed by Frank Nicholas on 12 Dec 2011
  • Changed by Frank Nicholas on 21 Mar 2012