OMIA 000202-476259 : Coat colour, oculocutaneous albinism type I (OCA1), TYR-related in Nyctereutes procyonoides viverrinus
Yamamoto et al. (2021) "analyzed TYR of another albino tanuki [Japanese raccoon dog] that was found in Matsusaka, a city located outside the mountainous area. In this animal, the third exon was also lost, and the loss was due to a deletion in which the structure was identical to that of the Iida mutant" described by Mae et al. (2020).Associated gene:
|Symbol||Description||Species||Chr||Location||OMIA gene details page||Other Links|
|TYR||Nyctereutes procyonoides viverrinus||-||no genomic information (-..-)||TYR||Ensembl|
By default, variants are sorted chronologically by year of publication, to provide a historical perspective. Readers can re-sort on any column by clicking on the column header. Click it again to sort in a descending order. To create a multiple-field sort, hold down Shift while clicking on the second, third etc relevant column headers.
WARNING! Inclusion of a variant in this table does not automatically mean that it should be used for DNA testing. Anyone contemplating the use of any of these variants for DNA testing should examine critically the relevant evidence (especially in breeds other than the breed in which the variant was first described). If it is decided to proceed, the location and orientation of the variant sequence should be checked very carefully.
|Breed(s)||Variant Phenotype||Gene||Allele||Type of Variant||Reference Sequence||Chr.||g. or m.||c. or n.||p.||Verbal Description||EVA ID||Year Published||PubMed ID(s)||Acknowledgements|
|albinism||TYR||complex rearrangement||Mae et al. (2020): "the third exon was removed due to a deletion ... :two separate regions of 3.8 kb and 7.3 kb had been removed, but a segment of 0.3 kb between these two regions was retained, though was present in the reverse orientation."||2020||32783776|
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
|2021||Yamamoto, S., Murase, M., Miyazaki, M., Hayashi, S., Koga, A. :|
|A mutant gene for albino body color is widespread in natural populations of tanuki (Japanese raccoon dog). Genes Genet Syst :, 2021. Pubmed reference: 33678735. DOI: 10.1266/ggs.20-00047.|
|2020||Mae, Y., Nagara, K., Miyazaki, M., Katsura, Y., Enomoto, Y., Koga, A. :|
|Complex intragene deletion leads to oculocutaneous albinism in tanuki (Japanese raccoon dog). Genome 63:517-523, 2020. Pubmed reference: 32783776. DOI: 10.1139/gen-2020-0049.|
- Created by Imke Tammen2 on 07 Apr 2021
- Changed by Imke Tammen2 on 07 Apr 2021
- Changed by Imke Tammen2 on 09 Apr 2021