OMIA 000683-9031 : Muscular hypertrophy (double muscling) in Gallus gallus

In other species: dog , pig , cattle

Mendelian trait/disorder: unknown

Considered a defect: no

Cross-species summary: Abnormal increase in muscular tissue caused entirely by enlargement of existing cells (in contrast to muscular hyperplasia, in which the abnormal increase in muscular tissue is due to the formation and growth of new, normal muscle cells)

Species-specific description: This is a genetically-modified organism; GMO

Associated gene:

Symbol Description Species Chr Location OMIA gene details page Other Links
MSTN myostatin Gallus gallus 7 NC_006094.5 (252348..257840) MSTN Homologene, Ensembl, NCBI gene


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
2018 Aiello, D., Patel, K., Lasagna, E. :
The myostatin gene: an overview of mechanisms of action and its relevance to livestock animals. Anim Genet :, 2018. Pubmed reference: 30125951. DOI: 10.1111/age.12696.
2016 Bhattacharya, T.K., Shukla, R., Chatterjee, R.N., Dushyanth, K. :
Knock down of the myostatin gene by RNA interference increased body weight in chicken. J Biotechnol :, 2016. Pubmed reference: 27845166. DOI: 10.1016/j.jbiotec.2016.11.012.
2002 Mott, I., Ivarie, R. :
Expression of myostatin is not altered in lines of poultry exhibiting myofiber hyper- and hypoplasia. Poult Sci 81:799-804, 2002. Pubmed reference: 12079046.

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  • Created by Frank Nicholas on 18 Nov 2016