Categories: Cardiovascular system phene

Possible human homologues (MIM numbers): 614429 (trait) , 614431 (trait) , 614432 (trait)

Cross-species summary: A congenital heart defect characterised by persistent patency (open-ness) of the ventricular septum, permitting flow of blood directly between ventricles, bypassing the pulmonary circulation and resulting in various degrees of cyanosis (blue discolouration of the skin) due to oxygen deficiency. Clinical signs include systolic murmur and a palpable thrill on both sides of the chest, dyspnoea and poor tolerance of exercise.

Species in which this phene is found:
chicken (Gallus gallus)
turkey (Meleagris gallopavo)
dog (Canis lupus familiaris)
domestic cat (Felis catus)
horse (Equus caballus)
pig (Sus scrofa)
taurine cattle (Bos taurus)
goat (Capra hircus)
sheep (Ovis aries)
rabbit (Oryctolagus cuniculus)
alpaca (Vicugna pacos)