OMIA 001199-9627 : Coat colour, extension in Vulpes vulpes
Liu et al. (2016) reported that "SNP c.373T>C in the coding region of the MC1R gene is probably associated with the brown phenotype of chocolate foxes".Associated gene:
|Symbol||Description||Species||Chr||Location||OMIA gene details page||Other Links|
|MC1R||Vulpes vulpes||-||no genomic information (-..-)||MC1R||Ensembl|
By default, variants are sorted chronologically by year of publication, to provide a historical perspective. Readers can re-sort on any column by clicking on the column header. Click it again to sort in a descending order. To create a multiple-field sort, hold down Shift while clicking on the second, third etc relevant column headers.
WARNING! Inclusion of a variant in this table does not automatically mean that it should be used for DNA testing. Anyone contemplating the use of any of these variants for DNA testing should examine critically the relevant evidence (especially in breeds other than the breed in which the variant was first described). If it is decided to proceed, the location and orientation of the variant sequence should be checked very carefully.
Since October 2021, OMIA includes a semiautomated lift-over pipeline to facilitate updates of genomic positions to a recent reference genome position. These changes to genomic positions are not always reflected in the ‘acknowledgements’ or ‘verbal description’ fields in this table.
|OMIA Variant ID||Breed(s)||Variant Phenotype||Gene||Allele||Type of Variant||Source of Genetic Variant||Reference Sequence||Chr.||g. or m.||c. or n.||p.||Verbal Description||EVA ID||Inferred EVA rsID||Year Published||PubMed ID(s)||Acknowledgements|
|115||Coat colour, extension||MC1R||missense||Naturally occurring variant||p.(C125R)||1997||9054949|
|116||Coat colour, extension||MC1R||missense||Naturally occurring variant||c.373C>T||p.(C125R)||2016||27072328|
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
|2016||Liu, Z., Gong, Y., Feng, M., Duan, L., Li, Y., Li, X. :|
|Genetic variations of the coding region of the melanocortin receptor 1 (MC1R) gene in the fox. Vet Dermatol 27:135-e36, 2016. Pubmed reference: 27072328. DOI: 10.1111/vde.12303.|
|2013||Nowacka-Woszuk, J., Salamon, S., Gorna, A., Switonski, M. :|
|Missense polymorphisms in the MC1R gene of the dog, red fox, arctic fox and Chinese raccoon dog. J Anim Breed Genet 130:136-41, 2013. Pubmed reference: 23496014. DOI: 10.1111/jbg.12005.|
|Switonski, M., Mankowska, M., Salamon, S. :|
|Family of melanocortin receptor (MCR) genes in mammals-mutations, polymorphisms and phenotypic effects. J Appl Genet 54:461-72, 2013. Pubmed reference: 23996627. DOI: 10.1007/s13353-013-0163-z.|
|1997||Vage, D.I., Lu, D.S., Klungland, H., Lien, S., Adalsteinsson, S., Cone, R.D. :|
|A non-epistatic interaction of agouti and extension in the fox, Vulpes vulpes Nature Genetics 15:311-315, 1997. Pubmed reference: 9054949. DOI: 10.1038/ng0397-311.|
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